Benedikt Saller

Doctoral Researcher
(Alumni)

Medical Center – University of Freiburg

Center for Pathology,
Institute for Neuropathology

currently PhD student in the lab of Prof. Olaf Groß, Institute of Neuropathology, Metabolism and Inflammation Research Group, Medical Center - University of Freiburg
2015 – 2017 M. Sc. in Molecular Biotechnology, Technical University of Munich, Germany
2011 – 2015 B. Sc. in Molecular Biotehcnology, Technical University of Munich, Germany

Publications

Schneider KS, Groß CJ, Dreier RF, Saller BS, …, Groß O (2017): The Inflammasome Drives GSDMD-Independent Secondary Pyroptosis and IL-1 Release in the Absence of Caspase-1 Protease Activity. In Cell Reports 21, pp. 3846–3859. DOI: 10.1016/j.celrep.2017.12.018.

Rieblinger B, Fischer K, Kind A, Saller BS, …, Schnieke A (2018): Strong xenoprotective function by single-copy transgenes placed sequentially at a permissive locus. In Xenotransplantation, 2018;25:e12382. DOI: 10.1111/xen.12382.

Publications based on CRC1160 funding

Vogele D, Wöhrle S, Saller BS, Fröhlich K, Barta BA, Cosenza-Contreras M, Groß O, Schilling O. 2024. Size exclusion chromatography based proteomic and degradomic profiling of inflammasome-activated, murine bone marrow-derived dendritic cells highlights complex retention and release of cleavage products. Mol Omics. 2024 Oct 28;20(9):595-610. doi: 10.1039/d4mo00163j.

Wertman RS, Yost W, Herrmann BI, Bourne CM, Sorobetea D, Go CK, Saller BS, Groß O, Scott P, Rongvaux A, Taabazuing CY, Brodsky IE. 2024. Distinct sequential death complexes regulate pyroptosis and IL-1β release in response to Yersinia blockade of immune signaling. Sci Adv. 10(30):eadl3629. doi: 10.1126/sciadv.adl3629.

Hamarsheh, S., L. Osswald, B. S. Saller, S. Unger, D. De Feo, J. M. Vinnakota, M. Konantz, F. M. Uhl, H. Becker, M. Lubbert, K. Shoumariyeh, C. Schurch, G. Andrieux, N. Venhoff, A. Schmitt-Graeff, S. Duquesne, D. Pfeifer, M. A. Cooper, C. Lengerke, M. Boerries, J. Duyster, C. M. Niemeyer, M. Erlacher, B. R. Blazar, B. Becher, O. Gross, T. Brummer, and R. Zeiser. 2020. Oncogenic Kras(G12D) causes myeloproliferation via NLRP3 inflammasome activation. Nat Commun 11: 1659.