Publications

Osborn MJ, Panda S, Reineke TM, Tolar J, Nyström A. 2025. Progress in skin gene therapy: From the inside and out. Mol Ther. Mar 12:S1525-0016(25)00191-1. doi: 10.1016/j.ymthe.2025.03.017.

Röttele F, Zollner A, Mogler C, Yuksel M, Arikan C, Karl V, Aberle JH, Aberle SW, Kogler H, Vécsei A, Vodopiutz J, Salié H, Gräser A, Krimmel L, Martin P, Lurz E, Maier FI, Woelfle L, Nobre S, Goncalves I, Kern L, Schwemmle M, Boettler T, Hofmann M, Hasselblatt P, Thimme R, Tilg H, Müller T, Vogel GF, Bengsch B. 2025.  Characteristic immune cell interactions in livers of children with acute hepatitis revealed by spatial single-cell analysis identify a possible postacute sequel of COVID-19. Gut. Apr 5:gutjnl-2024-333880. doi: 10.1136/gutjnl-2024-333880.

Schlösser RM, Krumbach F, Corrales E, Andrieux G, Preisinger C, Liss F, Golzmann A, Boerries M, Becker K, Knüchel R, Garczyk S, Lüscher B. 2025. Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal-like and malignant urothelial cells. Mol Oncol. Apr 1. doi: 10.1002/1878-0261.70019.

Zähringer A, Morgado I, Erny D, Ingelfinger F, Gawron J, Chatterjee S, Wenger V, Schmidt D, Schwöbel LF, Adams RC, Langenbach M, Hartmann A, Osswald N, Wolf J, Schlunck G, Briquez PS, Grueter K, Ruess DA, Frew I, Burk AC, Holzmüller V, Grimbacher B, Michonneau D, Andrieux G, Socié G, Kolter J, Börries M, Follo M, Blaeschke F, Sevenich L, Prinz M, Zeiser R, Vinnakota JM. 2025. AhR activation mitigates graft-versus-host disease of the central nervous system by reducing microglial NF-κB signaling. Blood Adv. Mar 31:bloodadvances.2024015000. doi: 10.1182/bloodadvances.2024015000.

Fernandez-Orth J, Koyunlar C, Weiss JM, Gioacchino E, de Looper HWJ, Andrieux G, Ter Borg M, Zink J, Gonzalez Menendez I, Hoogenboezem R, Yigit BI, Gussinklo K, Mulet-Lazaro R, Wantzen C, Pfeiffer S, Molnar C, Bindels E, Bohler S, Sanders MA, Quintanilla-Martinez L, Wlodarski MW, Boerries M, Touw IP, Niemeyer C, Erlacher M, de Pater E. 2025. Hematological phenotypes in GATA2 deficiency syndrome arise from aging maladaptation to proliferation and somatic events. Blood Adv. 2025 Mar 26:bloodadvances.2024015106. doi: 10.1182/bloodadvances.2024015106.

Andreev G, Vollmer T, Zirngibl M, Werner M, Grabbert M, Schilling O, Rogg M, Schell C. 2025. Spatial correlation of the extracellular matrix to immune cell phenotypes in the tumor boundary of ccRCC revealed by cyclic immunohistochemistry. Lab Invest. 2025 Mar 20:104130. doi: 10.1016/j.labinv.2025.104130.

Staniek J, Rizzi M. 2025. Signaling Activation and Modulation in Extrafollicular B Cell Responses. Immunol Rev. 330(1):e70004. doi: 10.1111/imr.70004.

Karl V, Hofmann M, Thimme R. 2025. Role of antiviral CD8+ T cell immunity to SARS-CoV-2 infection and vaccination. J Virol. Mar 3:e0135024. doi: 10.1128/jvi.01350-24.

Lösslein AK, Henneke P. 2025. Macrophage Differentiation and Metabolic Adaptation in Mycobacterial Infections. 2025. Annu Rev Immunol. doi: 10.1146/annurev-immunol-082323-120757.

Felixberger PT, Andrieux G, Maul-Pavicic A, Goldacker S, Harder I, Gutenberger S, Landry JJM, Benes V, Jakob TF, Boerries M, Nitschke L, Voll RE, Warnatz K, Keller B. 2025. CD21low B cells reveal a unique glycosylation pattern with hypersialylation and hyperfucosylation. Front Immunol. 16:1512279. doi: 10.3389/fimmu.2025.1512279.

Chandrasekaran P, Krausz M, Han Y, Mitsuiki N, Gabrysch A, Nöltner C, Proietti M, Heller T, Grou C, Calderon V, Subramanian P, Jones DR, Siu Y, Deming C, Conlan S, Holland SM, Segre JA, Uzel G, Grimbacher B, Falcone EL. 2025. The intestinal microbiome and metabolome discern disease severity in cytotoxic T-lymphocyte-associated protein 4 deficiency. Microbiome. 13(1):51. doi: 10.1186/s40168-025-02028-7.

Diehl R, Hübner S, Lehr S, Rizzi M, Eyerich K, Nyström A. 2025. Skin Deep and Beyond: Unravelling B Cell Extracellular Matrix Interactions in Cutaneous Immunity and Disease. Exp Dermatol. 34(3):e70068. doi: 10.1111/exd.70068.

Braun LM, Giesler S, Andrieux G, Riemer R, Talvard-Balland N, Duquesne S, Rückert T, Unger S, Kreutmair S, Zwick M, Follo M, Hartmann A, Osswald N, Melchinger W, Chapman S, Hutchinson JA, Haferkamp S, Torster L, Kött J, Gebhardt C, Hellwig D, Karantzelis N, Wallrabenstein T, Lowinus T, Yücel M, Brehm N, Rawluk J, Pfeifer D, Bronsert P, Rogg M, Mattern S, Heikenwälder M, Fusco S, Malek NP, Singer S, Schmitt-Graeff A, Ceteci F, Greten FR, Blazar BR, Boerries M, Köhler N, Duyster J, Ihorst G, Lassmann S, Keye P, Minguet S, Schadendorf D, Ugurel S, Rafei-Shamsabadi D, Thimme R, Hasselblatt P, Bengsch B, Schell C, Pearce EL, Meiss F, Becher B, Funke-Lorenz C, Placke JM, Apostolova P, Zeiser R. 2025. Adiponectin reduces immune checkpoint inhibitor-induced inflammation without blocking anti-tumor immunity. Cancer Cell. 2025 Feb 10;43(2):269-291.e19. doi: 10.1016/j.ccell.2025.01.004.

Nyström A. 2025. Dystrophic epidermolysis bullosa – From biochemistry to interventions. Matrix Biol. 2025 Apr;136:111-126. doi: 10.1016/j.matbio.2025.02.001.

Nyström A, Pattaroni C, Kern JS. 2025. The Role of Fibroblasts in Dystrophic Epidermolysis Bullosa Pathogenesis and Current Treatment Approaches. JID Innov. Feb 4;5(3):100353. doi: 10.1016/j.xjidi.2025.100353.

Mansoori Moghadam Z, Zhao B, Raynaud C RWTH University Hospital, Strohmeier V, Neuber J, Lösslein AK, Qureshi S, Gres V, Ziegelbauer T, Baasch S, Schell C, Warnatz K, Inohara N, Nunez G, Clavel T, Rosshart SP, Kolter J, Henneke P. 2025. Reactive oxygen species regulate early development of the intestinal macrophage-microbiome interface. Blood. blood.2024025240. doi: 10.1182/blood.2024025240.