Publications

Kiritsi D, Schauer F, Gewert S, Reineker K, Reimer-Taschenbrecker A, Schwieger-Briel A, Ott H, Schmoor C, Grishina O, Murrell D, Stiller B, Zahn T, Nyström A, Bruckner-Tuderman L. 2024.  Safety and tolerability of losartan to treat recessive dystrophic epidermolysis bullosa in children (REFLECT): an open-label, single-arm, phase 1/2 trial. EClinicalMedicine. 2024 Oct 30;77:102900. doi: 10.1016/j.eclinm.2024.102900.

Saller BS, Wöhrle S, Fischer L, Dufossez C, Ingerl IL, Kessler S, Mateo-Tortola M, Gorka O, Lange F, Cheng Y, Neuwirt E, Marada A, Koentges C, Urban C, Aktories P, Reuther P, Giese S, Kirschnek S, Mayer C, Pilic J, Falquez-Medina H, Oelgeklaus A, Deepagan VG, Shojaee F, Zimmermann JA, Weber D, Tai YH, Crois A, Ciminski K, Peyronnet R, Brandenburg KS, Wu G, Baumeister R, Heimbucher T, Rizzi M, Riedel D, Helmstädter M, Buescher J, Neumann K, Misgeld T, Kerschensteiner M, Walentek P, Kreutz C, Maurer U, Rambold AS, Vince JE, Edlich F, Malli R, Häcker G, Kierdorf K, Meisinger C, Köttgen A, Jakobs S, Weber ANR, Schwemmle M, Groß CJ, Groß O. 2024. Acute suppression of mitochondrial ATP production prevents apoptosis and provides an essential signal for NLRP3 inflammasome activation. Immunity. S1074-7613(24)00492-8. doi: 10.1016/j.immuni.2024.10.012.

Mann J, Runge S, Schell C, Gräwe K, Thoulass G, Lao J, Ammann S, Grün S, König C, Berger SA, Hild B, Aichele P, Rosshart SP, Ehl S. 2024. The Microbiome Modifies Manifestations of Hemophagocytic Lymphohistiocytosis in Perforin-Deficient Mice. Eur J Immunol. 2024 Nov 16:e202451061. doi: 10.1002/eji.202451061.

Giesler S, Riemer R, Lowinus T, Zeiser R. 2024. Immune-mediated colitis after immune checkpoint inhibitor therapy. Trends Mol Med. 2024 Oct 29:S1471-4914(24)00266-1. doi: 10.1016/j.molmed.2024.09.009.

Vogele D, Wöhrle S, Saller BS, Fröhlich K, Barta BA, Cosenza-Contreras M, Groß O, Schilling O. 2024. Size exclusion chromatography based proteomic and degradomic profiling of inflammasome-activated, murine bone marrow-derived dendritic cells highlights complex retention and release of cleavage products. Mol Omics. 2024 Oct 28;20(9):595-610. doi: 10.1039/d4mo00163j.

Minguet S, Maus MV, Schamel WW. 2024. From TCR fundamental research to innovative chimeric antigen receptor design. Nat Rev Immunol. 2024 Oct 21. doi: 10.1038/s41577-024-01093-7.

Hofmann M, Thimme R, Schamel WW. 2024. PD-1 and LAG-3: synergistic fostering of T cell exhaustion. Signal Transduct Target Ther. 2024 Oct 18;9(1):291. doi: 10.1038/s41392-024-02000-1.

Salié H, Wischer L, D’Alessio A, Godbole I, Suo Y, Otto-Mora P, Beck J, Neumann O, Stenzinger A, Schirmacher P, Fulgenzi CAM, Blaumeiser A, Boerries M, Roehlen N, Schultheiß M, Hofmann M, Thimme R, Pinato DJ, Longerich T, Bengsch B. 2024. Spatial single-cell profiling and neighbourhood analysis reveal the determinants of immune architecture connected to checkpoint inhibitor therapy outcome in hepatocellular carcinoma. Gut. Oct 14:gutjnl-2024-332837. doi: 10.1136/gutjnl-2024-332837.

Geiger RA, Khera D, Tenthorey JL, Kochs G, Graf L, Emerman M, Malik HS. 2024. Heterozygous and generalist MxA super-restrictors overcome breadth-specificity tradeoffs in antiviral restriction. bioRxiv [Preprint]. 2024 Oct 10:2024.10.10.617484. doi: 10.1101/2024.10.10.617484.

Dumas AA, Dalmau Gasull A, Prinz M. 2024. Beyond borders: the choroid plexus-immune communication during neuroinflammation. Signal Transduct Target Ther. 2024 Oct 8;9(1):278. doi: 10.1038/s41392-024-01997-9.

Wenger V, Zeiser R. 2024. Deciphering the role of the major histocompatibility complex, the intestinal microbiome and metabolites in the pathogenesis of acute graft-versus-host disease. Best Pract Res Clin Haematol. 2024 Sep;37(3):101567. doi: 10.1016/j.beha.2024.101567.

Grahammer F, Dumoulin B, Gulieva RE, Wu H, Xu Y, Sulaimanov N, Arnold F, Sandner L, Cordts T, Todkar A, Moulin P, Reichardt W, Puelles VG, Kramann R, Freedman BS, Busch H, Boerries M, Walz G, Huber TB. 2024. Cyclin-dependent kinase 4 drives cystic kidney disease in the absence of mTORC1 signaling activity. Kidney Int.: S0085-2538(24)00627-6. doi: 10.1016/j.kint.2024.08.021.

Heim K, Sagar, Sogukpinar Ö, Llewellyn-Lacey S, Price DA, Emmerich F, Kraft ARM, Cornberg M, Kielbassa S, Knolle P, Wohlleber D, Bengsch B, Boettler T, Neumann-Haefelin C, Thimme R, Hofmann M. 2024. Attenuated effector T cells are linked to control of chronic HBV infection. Nat Immunol. 25(9):1650-1662. doi: 10.1038/s41590-024-01928-4.

Schamel WW, Zinchenko M, Nguyen T, Fehse B, Briquez PS, Minguet S. 2024. The potential of γδ CAR and TRuC T cells: An unearthed treasure. Eur J Immunol. 2024 Aug 27:e2451074. doi: 10.1002/eji.202451074.

Frosch M, Prinz M. 2024. Novel pathomechanistic insights into lysosomal storage disorders: how neuron-intrinsic cGAS-STING signaling drives disease progression. Signal Transduct Target Ther. 9(1):203. doi: 10.1038/s41392-024-01901-5.

Wogram E, Sümpelmann F, Dong W, Rawat E, Fernández Maestre I, Fu D, Braswell B, Khalil A, Buescher JM, Mittler G, Borner GHH, Vlachos A, Tholen S, Schilling O, Bell GW, Rambold AS, Akhtar A, Schnell O, Beck J, Abu-Remaileh M, Prinz M, Jaenisch R. 2024. Rapid phagosome isolation enables unbiased multiomic analysis of human microglial phagosomes. Immunity. S1074-7613(24)00368-6. doi: 10.1016/j.immuni.2024.07.019.