Jonas Hummel

Dr.

Post-doctoral Researcher
(Alumni)

Institute for  Medical Microbiology
Center for Microbiology and Hygiene
Medical Center – University of Freiburg

Hermann Herder Str. 11
79104 Freiburg i. Brsg.

Postgraduate Positions

2015-present PostDoc in the lab of PD Dr. Yakup Tanriver, Institute for Microbiology and Hygiene, Medical Center – University Freiburg
2012-2015 PhD at the Institute of Virology and Immunobiology - University Wuerzburg

link to all publications from J. Hummel: Pubmed

Publications based on CRC1160 funding

Arnold F, Kupferschmid L, Weissenborn P, Heldmann L, Hummel JF, Zareba P, Sagar, Rogg M, Schell C, Tanriver Y. 2024. Tissue-resident memory T cells break tolerance to renal autoantigens and orchestrate immune-mediated nephritis. Cell Mol Immunol. Jul 3. doi: 10.1038/s41423-024-01197-z.

Moeed A, Thilmany N, Beck F, Puthussery BK, Ortmann N, Haimovici A, Badr MT, Haghighi EB, Boerries M, Öllinger R, Rad R, Kirschnek S, Gentle IE, Donakonda S, Petric PP, Hummel JF, Pfaffendorf E, Zanetta P, Schell C, Schwemmle M, Weber A, Häcker G. 2024. The Caspase-Activated DNase drives inflammation and contributes to defense against viral infection. Cell Death Differ. 2024 Jun 7. doi: 10.1038/s41418-024-01320-7.

Herr LA, Fiala GJ, Sagar, Schaffer AM, Hummel JF, Zintchenko M, Raute K, Velasco Cárdenas RM, Heizmann B, Ebert K, Fehrenbach K, Janowska I, Chan S, Tanriver Y, Minguet S, Schamel WW. 2024. Kidins220 and Aiolos promote thymic iNKT cell development by reducing TCR signals. Sci Adv. 10(11):eadj2802. doi: 10.1126/sciadv.adj2802.

Thelen B, Schipperges V, Knörlein P, Hummel JF, Arnold F, Kupferschmid L, Klose CSN, Arnold SJ, Boerries M, Tanriver Y. 2023. Eomes is sufficient to regulate IL-10 expression and cytotoxic effector molecules in murine CD4+ T cells. Front Immunol. 2023 Jan 19;14:1058267. doi: 10.3389/fimmu.2023.1058267.

Tanriver, U., F. Emmerich, J. F. Hummel, B. Janigen, M. Panning, F. Arnold, and Y. Tanriver. 2022. IFNL4 rs368234815 polymorphism does not predict risk of BK virus associated nephropathy after living-donor kidney transplant: A case-control study. Clin Transplant 36: e14663. doi: 10.1111/ctr.14663.

Fixemer J, Hummel JF, Arnold F, Klose CSN, Hofherr A, Weissert K, Kögl T, Köttgen M, Arnold SJ, Aichele P, Tanriver Y. 2020. Eomes cannot replace its paralog T-bet during expansion and differentiation of CD8 effector T cells. PLoS Pathog. 16(9):e1008870. doi: 10.1371/journal.ppat.1008870.

Hummel JF, Zeis P, Ebert K, Fixemer J, Konrad P, Schachtrup C, Arnold SJ, Grün D, Tanriver Y. 2019. Single-cell RNA-sequencing identifies the developmental trajectory of C-Myc-dependent NK1.1- T-bet+ intraepithelial lymphocyte precursors. Mucosal Immunol. doi: 10.1038/s41385-019-0220-y. [Epub ahead of print]

Klose CSN, Hummel JF, Faller L, d’Hargues Y, Ebert K, Tanriver Y. 2018. A committed postselection precursor to natural TCRαβ(+) intraepithelial lymphocytes. Mucosal Immunol. 11(2):333-344.

Probst S, Daza RA, Bader N, Hummel JF, Weiß M, Tanriver Y, Hevner RF, Arnold SJ. 2017. A dual-fluorescence reporter in the Eomes locus for live imaging and medium-term lineage tracing. Genesis. 55(8). doi: 10.1002/dvg.23043.