Post-doctoral Researcher
Medical Center – University of Freiburg
Department of Rheumatology and Clinical Immunology & Center for Chronic Immunodeficiency
- +49 (o) 761/ 203 – 35150
- julian.staniek@uniklinik-freiburg.de
- Homepage
| 04/2022 - present | Postdoc in the lab of Prof. Dr. Marta Rizzi, Center for Chronic Immunodeficiency (CCI) & Department of Internal Medicine, Rheumatology and Clinical Immunology, Medical Center - University of Freiburg |
| 2015 – 03/2022 | PhD student in the lab of Prof. Dr. Marta Rizzi, Center for Chronic Immunodeficiency (CCI) & Department of Internal Medicine, Rheumatology and Clinical Immunology, Medical Center - University of Freiburg |
| 2012 – 2014 | M. Sc. in Biology, University of Freiburg, Germany |
| 2008 – 2011 | B. Sc. in Biology, University of Tübingen, Germany |
Publications based on CRC1160 funding
Kögl T, Chang HF, Staniek J, Chiang SCC, Thoulass G, Lao J, Weißert K, Dettmer-Monaco V, Geiger K, Manna PT, Beziat V, Momenilandi M, Tu SM, Keppler SJ, Pattu V, Wolf P, Kupferschmid L, Tholen S, Covill LE, Ebert K, Straub T, Groß M, Gather R, Engel H, Salzer U, Schell C, Maier S, Lehmberg K, Cornu TI, Pircher H, Shahrooei M, Parvaneh N, Elling R, Rizzi M, Bryceson YT, Ehl S, Aichele P, Ammann S. 2024. Patients and mice with deficiency in the SNARE protein SYNTAXIN-11 have a secondary B cell defect. J Exp Med. 221(7):e20221122. doi: 10.1084/jem.20221122.
Thiel J, Schmidt FM, Lorenzetti R, Troilo A, Janowska I, Nießen L, Pfeiffer S, Staniek J, Benassini B, Bott MT, Korzhenevich J, Konstantinidis L, Burgbacher F, Dufner AK, Frede N, Voll RE, Stuchly J, Bakardjieva M, Kalina T, Smulski CR, Venhoff N, Rizzi M. 2024. Defects in B-lymphopoiesis and B-cell maturation underlie prolonged B-cell depletion in ANCA-associated vasculitis. Ann Rheum Dis. ard-2024-225587. doi: 10.1136/ard-2024-225587.
Kessler S, Burke B, Andrieux G, Schinköthe J, Hamberger L, Kacza J, Zhan S, Reasoner C, Dutt TS, Kaukab Osman M, Henao-Tamayo M, Staniek J, Villena Ossa JF, Frank DT, Ma W, Ulrich R, Cathomen T, Boerries M, Rizzi M, Beer M, Schwemmle M, Reuther P, Schountz T, Ciminski K. 2024. Deciphering bat influenza H18N11 infection dynamics in male Jamaican fruit bats on a single-cell level. Nat Commun. 2024 May 27;15(1):4500. doi: 10.1038/s41467-024-48934-6.
Staniek J, Kalina T, Andrieux G, Boerries M, Janowska I, Fuentes M, Díez P, Bakardjieva M, Stancikova J, Raabe J, Neumann J, Schwenk S, Arpesella L, Stuchly J, Benes V, García Valiente R, Fernández García J, Carsetti R, Piano Mortari E, Catala A, de la Calle O, Sogkas G, Neven B, Rieux-Laucat F, Magerus A, Neth O, Olbrich P, Voll RE, Alsina L, Allende LM, Gonzalez-Granado LI, Böhler C, Thiel J, Venhoff N, Lorenzetti R, Warnatz K, Unger S, Seidl M, Mielenz D, Schneider P, Ehl S, Rensing-Ehl A, Smulski CR, Rizzi M. 2024. Non-apoptotic FAS signaling controls mTOR activation and extrafollicular maturation in human B cells. Sci Immunol. Jan 12;9(91):eadj5948. doi: 10.1126/sciimmunol.adj5948.
Cox EM, El-Behi M, Ries S, Vogt JF, Kohlhaas V, Michna T, Manfroi B, Al-Maarri M, Wanke F, Tirosh B, Pondarre C, Lezeau H, Yogev N, Mittenzwei R, Descatoire M, Weller S, Weill JC, Reynaud CA, Boudinot P, Jouneau L, Tenzer S, Distler U, Rensing-Ehl A, König C, Staniek J, Rizzi M, Magérus A, Rieux-Laucat F, Wunderlich FT, Hövelmeyer N, Fillatreau S. 2023. AKT activity orchestrates marginal zone B cell development in mice and humans. Cell Rep. 2023 Apr 14;42(4):112378. doi: 10.1016/j.celrep.2023.112378.
Jacobsen, E. M., D. Fabricius, M. Class, F. Topfstedt, R. Lorenzetti, I. Janowska, F. Schmidt, J. Staniek, M. Zernickel, T. Stamminger, A. N. Dietz, A. Zellmer, M. Hecht, P. Rauch, C. Blum, C. Ludwig, B. Jahrsdorfer, H. Schrezenmeier, M. Heeg, B. Mayer, A. Seidel, R. Gross, J. Munch, F. Kirchhoff, S. F. N. Bode, G. Strauss, H. Renk, R. Elling, M. Stich, R.E. Voll, B. Tonshof, A. R. Franz, P. Henneke, K. M. Debatin, M. Rizzi, and A. Janda. 2022. High antibody levels and reduced cellular response in children up to one year after SARS-CoV-2 infection. Nat Commun 13: 7315. doi: 10.1038/s41467-022-35055-1.
Oberhardt V, Luxenburger H, Kemming J, Schulien I, Ciminski K, Giese S, Csernalabics B, Lang-Meli J, Janowska I, Staniek J, Wild K, Basho K, Marinescu MS, Fuchs J, Topfstedt F, Janda A, Sogukpinar O, Hilger H, Stete K, Emmerich F, Bengsch B, Waller CF, Rieg S, Sagar, Boettler T, Zoldan K, Kochs G, Schwemmle M, Rizzi M, Thimme R, Neumann-Haefelin C, Hofmann M. 2021. Rapid and stable mobilization of CD8+ T cells by SARS-CoV-2 mRNA vaccine. Nature. 28. doi: 10.1038/s41586-021-03841-4.
Kury, P., J. Staniek, O. Wegehaupt, I. Janowska, M. Eckenweiler, R. Korinthenberg, N. Japaridze, M. Pendziwiat, I. Helbig, E. Verhoeyen, J. Jung, A. C. Garcia de Oteyza, M. Proietti, T. Phirtskhalaishvili, I. Rtskhiladze, P. J. Nielsen, S. Ehl, C. Speckmann, and M. Rizzi. 2021. Agammaglobulinemia with normal B-cell numbers in a patient lacking Bob1. J Allergy Clin Immunol. S0091-6749(21)00174-3. doi: 10.1016/j.jaci.2021.01.027.
Maccari, M. E., S. Fuchs, P. Kury, G. Andrieux, S. Volkl, B. Bengsch, M. R. Lorenz, M. Heeg, J. Rohr, S. Jagle, C. N. Castro, M. Gross, U. Warthorst, C. Konig, I. Fuchs, C. Speckmann, J. Thalhammer, F. G. Kapp, M. G. Seidel, G. Duckers, S. Schonberger, C. Schutz, M. Fuhrer, R. Kobbe, D. Holzinger, C. Klemann, P. Smisek, S. Owens, G. Horneff, R. Kolb, N. Naumann-Bartsch, M. Miano, J. Staniek, M. Rizzi, T. Kalina, P. Schneider, A. Erxleben, R. Backofen, A. Ekici, C. M. Niemeyer, K. Warnatz, B. Grimbacher, H. Eibel, A. Mackensen, A. P. Frei, K. Schwarz, M. Boerries, S. Ehl, and A. Rensing-Ehl. 2021. A distinct CD38+CD45RA+ population of CD4+, CD8+, and double-negative T cells is controlled by FAS. J Exp Med 218(2):e20192191. doi: 10.1084/jem.20192191.
Troilo, A., C. Wehr, I. Janowska, N. Venhoff, J. Thiel, J. Rawluk, N. Frede, J. Staniek, R. Lorenzetti, M. T. Schleyer, G. W. Herget, L. Konstantinidis, M. Erlacher, M. Proietti, N. Camacho-Ordonez, R. E. Voll, B. Grimbacher, K. Warnatz, U. Salzer, and M. Rizzi. 2020. Nonpermissive bone marrow environment impairs early B-cell development in common variable immunodeficiency. Blood 135: 1452-1457.
Lorenzetti R, Janowska I, Smulski CR, Frede N, Henneberger N, Walter L, Schleyer MT, Hüppe JM, Staniek J, Salzer U, Venhoff A, Troilo A, Voll RE, Venhoff N, Thiel J, Rizzi M. 2019. Abatacept modulates CD80 and CD86 expression and memory formation in human B-cells. J Autoimmun. 101:145-152.
Staniek J, Lorenzetti R, Heller B, Janowska I, Schneider P, Unger S, Warnatz K, Seidl M, Venhoff N, Thiel J, Smulski CR, Rizzi M. 2019. TRAIL-R1 and TRAIL-R2 Mediate TRAIL-Dependent Apoptosis in Activated Primary Human B Lymphocytes. Front Immunol. 10:951.
Rizzi, M., R. Lorenzetti, K. Fischer, J. Staniek, I. Janowska, A. Troilo, V. Strohmeier, M. Erlacher, M. Kunze, B. Bannert, D. Kyburz, E. Voll, N. Venhoff, and J. Thiel. 2017. Impact of tofacitinib treatment on human B-cells in vitro and in vivo. J Autoimmun 77: 55-66.
