Post-doctoral Researcher
(Alumni)
University of Freiburg
Department of Medical Microbiology and Hygiene, Institute for Immunology
since October 2021 | Postdoctoral research associate in the lab of Dr. Peter Aichele, Institute for Immunology, Department of Medical Microbiology and Hygiene, Medical Center - University of Freiburg |
2016 – September 2021 | PhD student in the lab of Dr. Peter Aichele, Institute for Immunology, Department of Medical Microbiology and Hygiene, Medical Center - University of Freiburg |
2013 – 2016 | M. Sc. in Biology, specialization in Immunology, University of Freiburg, Germany |
2010 – 2013 | B. Sc. in Biological Sciences, University of Konstanz, Germany |
Publications based on CRC1160 funding
Kögl T, Chang HF, Staniek J, Chiang SCC, Thoulass G, Lao J, Weißert K, Dettmer-Monaco V, Geiger K, Manna PT, Beziat V, Momenilandi M, Tu SM, Keppler SJ, Pattu V, Wolf P, Kupferschmid L, Tholen S, Covill LE, Ebert K, Straub T, Groß M, Gather R, Engel H, Salzer U, Schell C, Maier S, Lehmberg K, Cornu TI, Pircher H, Shahrooei M, Parvaneh N, Elling R, Rizzi M, Bryceson YT, Ehl S, Aichele P, Ammann S. 2024. Patients and mice with deficiency in the SNARE protein SYNTAXIN-11 have a secondary B cell defect. J Exp Med. 221(7):e20221122. doi: 10.1084/jem.20221122.
Dettmer-Monaco V, Weißert K, Ammann S, Monaco G, Lei L, Gräßel L, Rhiel M, Rositzka J, Kaufmann MM, Geiger K, Andrieux G, Lao J, Thoulass G, Schell C, Boerries M, Illert AL, Cornu TI, Ehl S, Aichele P, Cathomen T. 2024. Gene editing of hematopoietic stem cells restores T-cell response in familial hemophagocytic lymphohistiocytosis. J Allergy Clin Immunol. Jan;153(1):243-255.e14. doi: 10.1016/j.jaci.2023.08.003.
Kemna J, Gout E, Daniau L, Lao J, Weißert K, Ammann S, Kühn R, Richter M, Molenda C, Sporbert A, Zocholl D, Klopfleisch R, Lortat-Jacob H, Aichele P, Kammertoens T, Blankenstein T. 2023. IFNγ binding to extracellular matrix prevents fatal systemic toxicity. Nat Immunol. 24, 414–422. doi.org/10.1038/s41590-023-01420-5
Weissert, K., S. Ammann, T. Kogl, V. Dettmer-Monaco, C. Schell, T. Cathomen, S. Ehl, and P. Aichele. 2022. Adoptive T cell therapy cures mice from active hemophagocytic lymphohistiocytosis (HLH). EMBO Mol Med: e16085. doi: 10.15252/emmm.202216085.
Fixemer J, Hummel JF, Arnold F, Klose CSN, Hofherr A, Weissert K, Kögl T, Köttgen M, Arnold SJ, Aichele P, Tanriver Y. 2020. Eomes cannot replace its paralog T-bet during expansion and differentiation of CD8 effector T cells. PLoS Pathog. 16(9):e1008870. doi: 10.1371/journal.ppat.1008870.
Dettmer, V., K. Bloom, M. Gross, K. Weissert, Aichele, S. Ehl, and T. Cathomen. 2019. Retroviral UNC13D gene transfer restores cytotoxic activity of T cells derived from familial hemophagocytic lymphohistiocytosis type 3 patients in vitro. Hum Gene Ther. 30(8): 975-984.