News

Prof. Dr. Robert Zeiser (B09) receives the 2024 DKMS Mechthild Harf Science Award from the DKMS Stiftung Leben Spenden (Foundation for Giving Life) as honour for his outstanading research work in the field of allogeneic stem cell transplantation. With the DKMS Mechtild Harf Science Award, the foundation honours the lifetime achievements of internationally renowned physicians and scientists in the field of stem cell transplantation and cellular therapies.

The two cross-border projects will strengthen cooperation between Strasbourg and Freiburg.

CRC 1160 member Susana Minguet (B01) investigates the effect of a novel mutation in Lck on TCR signaling, T-cell function, and differentiation in patients with combined immunodeficiency (CID).

When autoimmune diseases occur in childhood and are accompanied by swollen lymph glands or an enlarged spleen, this indicates a congenital disorder of the immune system. The exact diagnosis is difficult, but crucial for therapy. A study by  Stephan Ehl (A01) at the the Centre for Chronic Immunodeficiency, Medical Center – University of Freiburg has now provided new insights into autoimmune lymphoproliferative diseases in children.

The findings of the CRC 1160 member, Susana Minguet (B01), address an important question and provide some clear directions for the use of the λ-chain locus.

A new study, led by CRC 1160 member Marta Rizzi (B02), relates classic disease markers – such as dysfunctional B cell differentiation – to a pathway triggered by non-apoptotoc signaling from the FAS protein

Gamma-delta T cells represent a distinctive subset within the T cell family, and their implications in cancer have been under rigorous investigation. A recent study, led by CRC 1160 member Sagar (B08 and Z02), involved researchers from the Medical Center – University of Freiburg, including Maike Hofmann (CRC 1160, A02) and Robert Thimme (CRC 1160, A02), and Institut Curie Paris, shedding light on the diversity and tissue residency of gamma-delta T cells across various organs in mice.

Save the date!
Prof. Dr. Rita Carsetti (Bambino Gesu Children’s Hospital, Rome, Italy) will talk about “Memory B cells in Health and Disease” on November 13, 2023.

CAR-T cell therapy is a last hope for many patients with blood, bone marrow or lymph gland cancer when other treatments such as chemotherapy are unsuccessful. A limiting factor of this otherwise very effective and safe therapy is that the cells used in the process quickly reach a state of exhaustion. Susana Minguet (B01) and Wolfgang Schamel (University of Freiburg) have now been able to prevent this exhaustion and thus significantly improve the effect of the therapy in a preclinical animal model. The new results have been published in the journal Nature Immunology.

Celebrating 10 years of empowering women “Flying to new heights with kite-mentoring” – joined with the International Conference of eument-net.

Physical and mental health go hand in hand – that’s why the University Health Day at the University of Freiburg is dedicated to numerous topics such as mindfulness healthy eating and sleep, stress management and multitasking within a framework of lectures, information booths and workshops.
Registration for workshops is now open.

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Dr. Maike Hofmann, scientist of the CRC 1160 (A02), has been accepted into the Heisenberg Programme from the German Research Foundation (DFG).

Marta Rizzi (B02) has taken on a Heisenberg professorship at the University of Freiburg on April 1, 2023 with a research focus on immunodeficiencies

DFG granted 3. Funding period for CRC 1160.

We are proud and happy and are looking forward to the next 4 years of research.