Department for Medical Microbiology and Hygiene
Institute for Immunology
Medical Center – University of Freiburg
Hermann Herder Str. 11
79104 Freiburg i. Brsg.
- +49 (0) 761/ 270 – 6521
- hanspeter.pircher@uniklinik-freiburg.de
- Homepage
Current position
Professor, Head of the Institute for Immunology, Center for Microbiology and Hygiene, Medical Center – University of Freiburg
Academic training
1976 – 1981 | Study of Biochemistry, ETH Zurich, Switzerland |
Scientific qualifications
1993 | Habilitation in Exp. Immunology, University of Zurich, Switzerland (Mentor: Prof. Rolf Zinkernagel) |
1985 | PhD Thesis, ETH/University Hospital Zurich, Switzerland (Supervisor: Prof. Hans Hengartner) |
Postgraduate Positions
since 1995 | C3 Professor and Head of the Institute for Immunology, Center for Microbiology and Hygiene, Medical Center – University of Freiburg |
1988 – 1995 | Research Fellow, Institute of Experimental Immunology, University of Zurich, Switzerland |
1986 – 1987 | Postdoctorate, Ontario Cancer Institute, Toronto, Canada |
Miscellaneous (Honors, Awards)
2015 - 2017 | Deputy Speaker SFB 1160 |
2009 – 2013 | Speaker SFB 620 |
2002 – 2009 | Deputy Speaker SFB 620 |
Publications based on CRC1160 funding
Kögl T, Chang HF, Staniek J, Chiang SCC, Thoulass G, Lao J, Weißert K, Dettmer-Monaco V, Geiger K, Manna PT, Beziat V, Momenilandi M, Tu SM, Keppler SJ, Pattu V, Wolf P, Kupferschmid L, Tholen S, Covill LE, Ebert K, Straub T, Groß M, Gather R, Engel H, Salzer U, Schell C, Maier S, Lehmberg K, Cornu TI, Pircher H, Shahrooei M, Parvaneh N, Elling R, Rizzi M, Bryceson YT, Ehl S, Aichele P, Ammann S. 2024. Patients and mice with deficiency in the SNARE protein SYNTAXIN-11 have a secondary B cell defect. J Exp Med. 221(7):e20221122. doi: 10.1084/jem.20221122.
Gather, R., P. Aichele, N. Goos, J. Rohr, H. Pircher, T. Kogl, R. Zeiser, H. Hengel, A. Schmitt-Graff, C. Weaver, and S. Ehl. 2020. Trigger-dependent differences determine therapeutic outcome in murine primary hemophagocytic lymphohistiocytosis. Eur J Immunol. doi: 10.1002/eji.201948123. [Epub ahead of print].
Schweier, O., U. Aichele, A. F. Marx, T. Straub, J. S. Verbeek, D. D. Pinschewer, and H. Pircher. 2019. Residual LCMV antigen in transiently CD4(+) T cell-depleted mice induces high levels of virus-specific antibodies but only limited B-cell memory. Eur J Immunol 49: 626-637.
Straub T, Pircher H. 2019. Enhancing immunity prevents virus-induced T-cell-mediated immunopathology in B cell-deficient mice. Eur J Immunol. 49(5):782-789.
Schuch A, Zecher BF, Müller PA, Correia MP, Daul F, Rennert C, Tauber C, Schlitt K, Boettler T, Neumann-Haefelin C, Hengel H, Pircher H, Cerwenka A, Thimme R, Hofmann M. 2019. NK-cell responses are biased towards CD16-mediated effector functions in chronic hepatitis B virus infection. J Hepatol. 70(3):351-360.
Straub, T., M. A. Freudenberg, U. Schleicher, C. Bogdan, G. Gasteiger, and Pircher. 2018. Bacterial coinfection restrains antiviral CD8 T-cell response via LPS-induced inhibitory NK cells. Nat Commun 9: 4117.
Hofmann, M., D. Wieland, Pircher, and R. Thimme. 2018. Memory vs memory-like: The different facets of CD8(+) T-cell memory in HCV infection. Immunol Rev 283: 232-237.
Woopen C, Straub T, Schweier O, Aichele U, Düker K, Boehm T, Pircher H. 2018. Immunological tolerance to LCMV antigens differently affects control of acute and chronic virus infection in mice. Eur J Immunol. 48(1):120-127.