Center for Pediatrics
Department of General Pediatrics, Adolescent Medicine and Neonatology &
Center for Chronic Immunodeficiency
Medical Center – University of Freiburg
Breisacher Str. 117, 2.OG
79106 Freiburg i. Brsg.
- +49 (0) 761/ 270 – 43090
- jan.rohr@uniklinik-freiburg.de
- Homepage
Current position
Assistant physician and Junior Group leader, Center for Pediatrics and Center for Chronic Immunodeficiency, Medical Center – University of Freiburg
Academic training
| 1997 – 2004 | Study of Medicine in Greifswald, Homburg and Heidelberg |
Scientific qualifications
| 2004 | Dissertation in Medicine, University of Mainz (Supervisor: Prof. F. Zepp) |
Postgraduate Positions
| since 2014 | Assistant physician and Junior Group leader, Center for Pediatrics and Center for Chronic Immunodeficiency, Medical Center - University of Freiburg |
| 2010 – 2013 | Postdoctorate, Department of Immunology, The Netherlands Cancer Institute (NKI-AVL), Amsterdam, The Netherlands |
| 2004 – 2010 | Assistant physician in Division of General Pediatrics and Adolescent Medicine, Medical Center - University of Freiburg |
Miscellaneous (Honors, Awards)
| 2011 | Research Fellowship (Deutsche Forschungsgemeinschaft (DFG)) |
| 2010 | Walter-Hitzig Fellowship (Center for Chronic Immunodeficiency, Freiburg) |
Publications based on CRC1160 funding
Rojas-Restrepo J, Sindram E, Zenke S, Haberstroh H, Mitsuiki N, Gabrysch A, Huebscher K, Posadas-Cantera S, Krausz M, Kobbe R, Rohr JC, Grimbacher B, Gámez-Díaz L. 2023. Functional Relevance of CTLA4 Variants: an Upgraded Approach to Assess CTLA4-Dependent Transendocytosis by Flow Cytometry. J Clin Immunol. doi: 10.1007/s10875-023-01582-9.
Zink A, Zenke S, Wiese T, Beyersdorf N, Lämmermann T, Rohr JC. 2023. Analyzing trogocytosis of T lymphocytes by flow cytometry and confocal microscopy. STAR Protoc. Jan 11;4(1):102013. doi: 10.1016/j.xpro.2022.102013.
Maccari, M. E., S. Fuchs, P. Kury, G. Andrieux, S. Volkl, B. Bengsch, M. R. Lorenz, M. Heeg, J. Rohr, S. Jagle, C. N. Castro, M. Gross, U. Warthorst, C. Konig, I. Fuchs, C. Speckmann, J. Thalhammer, F. G. Kapp, M. G. Seidel, G. Duckers, S. Schonberger, C. Schutz, M. Fuhrer, R. Kobbe, D. Holzinger, C. Klemann, P. Smisek, S. Owens, G. Horneff, R. Kolb, N. Naumann-Bartsch, M. Miano, J. Staniek, M. Rizzi, T. Kalina, P. Schneider, A. Erxleben, R. Backofen, A. Ekici, C. M. Niemeyer, K. Warnatz, B. Grimbacher, H. Eibel, A. Mackensen, A. P. Frei, K. Schwarz, M. Boerries, S. Ehl, and A. Rensing-Ehl. 2021. A distinct CD38+CD45RA+ population of CD4+, CD8+, and double-negative T cells is controlled by FAS. J Exp Med 218(2):e20192191. doi: 10.1084/jem.20192191.
Gather, R., P. Aichele, N. Goos, J. Rohr, H. Pircher, T. Kogl, R. Zeiser, H. Hengel, A. Schmitt-Graff, C. Weaver, and S. Ehl. 2020. Trigger-dependent differences determine therapeutic outcome in murine primary hemophagocytic lymphohistiocytosis. Eur J Immunol. doi: 10.1002/eji.201948123. [Epub ahead of print].
Zenke S, Palm MM, Braun J, Gavrilov A, Meiser P, Böttcher JP, Beyersdorf N, Ehl S, Gerard A, Lämmermann T, Schumacher TN, Beltman JB, Rohr JC. 2020. Quorum Regulation via Nested Antagonistic Feedback Circuits Mediated by the Receptors CD28 and CTLA-4 Confers Robustness to T Cell Population Dynamics. Immunity. 52(2):313-327.e7.
Prestipino A, Emhardt AJ, Aumann K, O’Sullivan D, Gorantla SP, Duquesne S,Melchinger W, Braun L, Vuckovic S, Boerries M, Busch H, Halbach S, Pennisi S, Poggio T, Apostolova P, Veratti P, Hettich M, Niedermann G, Bartholomä M,Shoumariyeh K, Jutzi JS, Wehrle J, Dierks C, Becker H, Schmitt-Graeff A, Follo M, Pfeifer D, Rohr J, Fuchs S, Ehl S, Hartl FA, Minguet S, Miething C, Heidel FH, Kröger N, Triviai I, Brummer T, Finke J, Illert AL, Ruggiero E, Bonini C, Duyster J, Pahl HL, Lane SW, Hill GR, Blazar BR, von Bubnoff N, Pearce EL, Zeiser R. 2018. Oncogenic JAK2(V617F) causes PD-L1 expression, mediating immune escape in myeloproliferative neoplasms. Sci Transl Med. 10(429). pii:eaam7729.
Klemann C, Ammann S, Heizmann M, Fuchs S, Bode SF, Heeg M, Fuchs H, Lehmberg K, Zur Stadt U, Roll C, Vraetz T, Speckmann C, Lorenz MR, Schwarz K, Rohr J, Feske S, Ehl S. 2017. Hemophagocytic lymphohistiocytosis as presenting manifestation of profound combined immunodeficiency due to an ORAI1 mutation. J Allergy Clin Immunol. 140(6):1721-1724.
