Katrin Kierdorf

Jun.-Prof. Dr.
Principal Investigator

Institute of Neuropathology, IMITATE
Medical Center – University of Freiburg

Breisacher Str. 113
79106 Freiburg i. Brsg.

Current position

Juniorprofessor for Neuroimmunology, Medical Faculty, University of Freiburg

Academic training

2004 – 2008 Molecular Biomedicine (Diploma studies), University of Bonn, Bonn, Germany

Scientific qualifications

2013 Dr. rer. nat., Molecular Medicine, University of Freiburg, Freiburg im Breisgau, Germany

Postgraduate Positions

Since 11/2017 W1 Professor for Neuroimmunology, Institute of Neuropathology, University of Freiburg, Germany
2015–2017 Research Associate, Prof. Dr. Marc S. Dionne, MRC Centre for Molecular Bacteriology and Infection, Imperial College London, United Kingdom
2013–2015 Research Associate, Prof. Dr. Frederic Geissmann, Centre for Molecular and Cellular Biology of Inflammation, King’s College London, United Kingdom
2013 Research Associate, Prof. Dr. Marco Prinz, Institute of Neuropathology, University Freiburg, Germany

Miscellaneous (Honors, Awards)

2022 Awardee Rising Star Initiative, ONO Pharmaceutical Co., Ltd.
2014-2016 Postdoctoral Fellowship, German Research Foundation (DFG)
2014 GeFI Award Recipient, Freiburg
2013 Herbert-Fischer-Award, German Society of Immunology (DGfI)

link to all publications from K. Kierdorf: Pubmed

Publications based on CRC1160 funding

Saller BS, Wöhrle S, Fischer L, Dufossez C, Ingerl IL, Kessler S, Mateo-Tortola M, Gorka O, Lange F, Cheng Y, Neuwirt E, Marada A, Koentges C, Urban C, Aktories P, Reuther P, Giese S, Kirschnek S, Mayer C, Pilic J, Falquez-Medina H, Oelgeklaus A, Deepagan VG, Shojaee F, Zimmermann JA, Weber D, Tai YH, Crois A, Ciminski K, Peyronnet R, Brandenburg KS, Wu G, Baumeister R, Heimbucher T, Rizzi M, Riedel D, Helmstädter M, Buescher J, Neumann K, Misgeld T, Kerschensteiner M, Walentek P, Kreutz C, Maurer U, Rambold AS, Vince JE, Edlich F, Malli R, Häcker G, Kierdorf K, Meisinger C, Köttgen A, Jakobs S, Weber ANR, Schwemmle M, Groß CJ, Groß O. 2024. Acute suppression of mitochondrial ATP production prevents apoptosis and provides an essential signal for NLRP3 inflammasome activation. Immunity. S1074-7613(24)00492-8. doi: 10.1016/j.immuni.2024.10.012.

Petry P, Aktories P, Oschwald A, Kierdorf K. 2024. Protocol for long-term monocultures of murine macrophages derived from distinct adult tissues. STAR Protoc. 5(3):103145. doi: 10.1016/j.xpro.2024.103145.

Vinnakota JM, Biavasco F, Schwabenland M, Chhatbar C, Adams RC, Erny D, Duquesne S, El Khawanky N, Schmidt D, Fetsch V, Zähringer A, Salié H, Athanassopoulos D, Braun LM, Javorniczky NR, Ho JNHG, Kierdorf K, Marks R, Wäsch R, Simonetta F, Andrieux G, Pfeifer D, Monaco G, Capitini C, Fry TJ, Blank T, Blazar BR, Wagner E, Theobald M, Sommer C, Stelljes M, Reicherts C, Jeibmann A, Schittenhelm J, Monoranu CM, Rosenwald A, Kortüm M, Rasche L, Einsele H, Meyer PT, Brumberg J, Völkl S, Mackensen A, Coras R, von Bergwelt-Baildon M, Albert NL, Bartos LM, Brendel M, Holzgreve A, Mack M, Boerries M, Mackall CL, Duyster J, Henneke P, Priller J, Köhler N, Strübing F, Bengsch B, Ruella M, Subklewe M, von Baumgarten L, Gill S, Prinz M, Zeiser R. 2024. Targeting TGFβ-activated kinase-1 activation in microglia reduces CAR T immune effector cell-associated neurotoxicity syndrome. Nat Cancer. May 13. doi: 10.1038/s43018-024-00764-7.

Hersperger F, Meyring T, Weber P, Chhatbar C, Monaco G, Dionne MS, Paeschke K, Prinz M, Groß O, Classen AK, Kierdorf K. 2024. DNA damage signaling in Drosophila macrophages modulates systemic cytokine levels in response to oxidative stress. Elife. 2024 Jan 8;12:RP86700. doi: 10.7554/eLife.86700.

Mass E, Nimmerjahn F, Kierdorf K, Schlitzer A. 2023. Tissue-specific macrophages: how they develop and choreograph tissue biology.  Nat Rev Immunol.  Mar 15:1-17. doi: 10.1038/s41577-023-00848-y.