Marco Prinz

Dumas AA, Dalmau Gasull A, Prinz M. 2024. Beyond borders: the choroid plexus-immune communication during neuroinflammation. Signal Transduct Target Ther. 2024 Oct 8;9(1):278. doi: 10.1038/s41392-024-01997-9.

Frosch M, Prinz M. 2024. Novel pathomechanistic insights into lysosomal storage disorders: how neuron-intrinsic cGAS-STING signaling drives disease progression. Signal Transduct Target Ther. 9(1):203. doi: 10.1038/s41392-024-01901-5.

Wogram E, Sümpelmann F, Dong W, Rawat E, Fernández Maestre I, Fu D, Braswell B, Khalil A, Buescher JM, Mittler G, Borner GHH, Vlachos A, Tholen S, Schilling O, Bell GW, Rambold AS, Akhtar A, Schnell O, Beck J, Abu-Remaileh M, Prinz M, Jaenisch R. 2024. Rapid phagosome isolation enables unbiased multiomic analysis of human microglial phagosomes. Immunity. S1074-7613(24)00368-6. doi: 10.1016/j.immuni.2024.07.019.

Kuehn JC, Metzger P, Neidert N, Matysiak U, Gräßel L, Philipp U, Bleul S, Pauli T, Falkenstein J, Bertemes H, Cysar S, Hess ME, Frey AV, Duque-Afonso J, Schorb E, Machein M, Beck J, Schnell O, von Bubnoff N, Illert AL, Peters C, Brummer T, Prinz M, Miething C, Becker H, Lassmann S, Werner M, Börries M, Duyster J, Heiland DH, Sankowski R, Scherer F. 2024. Comprehensive genetic profiling and molecularly guided treatment for patients with primary CNS tumors. NPJ Precis Oncol. 2024 Aug 14;8(1):180. doi: 10.1038/s41698-024-00674-y.

Vinnakota JM, Biavasco F, Schwabenland M, Chhatbar C, Adams RC, Erny D, Duquesne S, El Khawanky N, Schmidt D, Fetsch V, Zähringer A, Salié H, Athanassopoulos D, Braun LM, Javorniczky NR, Ho JNHG, Kierdorf K, Marks R, Wäsch R, Simonetta F, Andrieux G, Pfeifer D, Monaco G, Capitini C, Fry TJ, Blank T, Blazar BR, Wagner E, Theobald M, Sommer C, Stelljes M, Reicherts C, Jeibmann A, Schittenhelm J, Monoranu CM, Rosenwald A, Kortüm M, Rasche L, Einsele H, Meyer PT, Brumberg J, Völkl S, Mackensen A, Coras R, von Bergwelt-Baildon M, Albert NL, Bartos LM, Brendel M, Holzgreve A, Mack M, Boerries M, Mackall CL, Duyster J, Henneke P, Priller J, Köhler N, Strübing F, Bengsch B, Ruella M, Subklewe M, von Baumgarten L, Gill S, Prinz M, Zeiser R. 2024. Targeting TGFβ-activated kinase-1 activation in microglia reduces CAR T immune effector cell-associated neurotoxicity syndrome. Nat Cancer. May 13. doi: 10.1038/s43018-024-00764-7.

Sankowski R, Prinz M. 2024. Microglia out of place-mapping macrophages across the developing human body. Cell Mol Immunol. 21(3):210-212. doi: 10.1038/s41423-023-01100-2.

Dalmau Gasull A, Glavan M, Samawar SKR, Kapupara K, Kelk J, Rubio M, Fumagalli S, Sorokin L, Vivien D, Prinz M. 2024. The niche matters: origin, function and fate of CNS-associated macrophages during health and disease. Acta Neuropathol. 147(1):37. doi: 10.1007/s00401-023-02676-9.

Hersperger F, Meyring T, Weber P, Chhatbar C, Monaco G, Dionne MS, Paeschke K, Prinz M, Groß O, Classen AK, Kierdorf K. 2024. DNA damage signaling in Drosophila macrophages modulates systemic cytokine levels in response to oxidative stress. Elife. 2024 Jan 8;12:RP86700. doi: 10.7554/eLife.86700.

Sankowski R, Süß P, Benkendorff A, Böttcher C, Fernandez-Zapata C, Chhatbar C, Cahueau J, Monaco G, Gasull AD, Khavaran A, Grauvogel J, Scheiwe C, Shah MJ, Heiland DH, Schnell O, Markfeld-Erol F, Kunze M, Zeiser R, Priller J, Prinz M. 2023. Multiomic spatial landscape of innate immune cells at human central nervous system borders. Nat Med. 2023 Dec 20. doi: 10.1038/s41591-023-02673-1.

Wogram E, Prinz M. 2023. APOE set the microglia free. Nat Immunol. 24(11):1790-1791. doi: 10.1038/s41590-023-01651-6.

Faust, T. E., P. A. Feinberg, C. O’Connor, R. Kawaguchi, A. Chan, H. Strasburger, M. Frosch, M. A. Boyle, T. Masuda, L. Amann, K. P. Knobeloch, Prinz, A. Schaefer, and D. P. Schafer. 2023. A comparative analysis of microglial inducible Cre lines. Cell Rep 42: 113031. doi: 10.1016/j.celrep.2023.113031.

Macpherson, A. J., V. Pachnis, and Prinz. 2023. Boundaries and integration between microbiota, the nervous system, and immunity. Immunity 56: 1712-1726. doi: 10.1016/j.immuni.2023.07.011.

Gulen MF, Samson N, Keller A, Schwabenland M, Liu C, Glück S, Thacker VV, Favre L, Mangeat B, Kroese LJ, Krimpenfort P, Prinz M, Ablasser A. 2023. cGAS-STING drives ageing-related inflammation and neurodegeneration. Nature. 620(7973):374-380. doi: 10.1038/s41586-023-06373-1.

Frosch M, Amann L, Prinz M. 2023. CNS-associated macrophages shape the inflammatory response in a mouse model of Parkinson’s disease. Nat Commun. 2023 Jun 26;14(1):3753. doi: 10.1038/s41467-023-39061-9.

Amann L, Masuda T, Prinz M. Mechanisms of myeloid cell entry to the healthy and diseased central nervous system. Nat Immunol. 2023 Feb 9. doi: 10.1038/s41590-022-01415-8.

Ferrarese, R., A. Izzo, G. Andrieux, S. Lagies, J. P. Bartmuss, A. P. Masilamani, A. Wasilenko, D. Osti, S. Faletti, R. Schulzki, S. Yuan, E. Kling, V. Ribecco, D. H. Heiland, S. Tholen, Prinz, G. Pelicci, B. Kammerer, M. Boerries, and M. S. Carro. 2023. ZBTB18 inhibits SREBP-dependent lipid synthesis by halting CTBPs and LSD1 activity in glioblastoma. Life Sci Alliance 6: e202201400. doi: 10.26508/lsa.202201400.

Locatelli, G., F. Marques-Ferreira, A. Katsoulas, V. Kalaitzaki, M. Krueger, B. Ingold-Heppner, S. Walthert, R. Sankowski, O. Prazeres da Costa, A. Dolga, M. Huber, M. Gold, C. Culmsee, A. Waisman, I. Bechmann, V. Milchevskaya, M. Prinz, A. Tresch, B. Becher, and T. Buch. 2022. IGF1R expression by adult oligodendrocytes is not required in the steady-state but supports neuroinflammation. Glia. doi: 10.1002/glia.24299. doi: 10.1002/glia.24299.

Cook, J., and M. Prinz. 2022. Regulation of microglial physiology by the microbiota. Gut Microbes 14: 2125739. doi: 10.1080/19490976.2022.2125739.

Aktories, P., P. Petry, P. Glatz, G. Andrieux, A. Oschwald, H. Botterer, O. Gorka, D. Erny, M. Boerries, P. Henneke, O. Gross, M. Prinz, and K. Kierdorf. 2022. An improved organotypic cell culture system to study tissue-resident macrophages ex vivo. Cell Rep Methods 2: 100260. doi: 10.1016/j.crmeth.2022.100260.

Friedrich M, Hahn M, Michel J, Sankowski R, Kilian M, Kehl N, Günter M, Bunse T, Pusch S, von Deimling A, Wick W, Autenrieth SE, Prinz M, Platten M, Bunse L. Neuro Oncol. 2022. Dysfunctional dendritic cells limit antigen-specific T cell response in glioma. First Published: 2022 May 24:noac138. doi: 10.1093/neuonc/noac138.

Kolter J, Henneke P, Groß O, Kierdorf K, Prinz M, Graf L, Schwemmle M. 2022. Paradoxical immunodeficiencies-When failures of innate immunity cause immunopathology. Eur J Immunol. First published: 2022 May 12. doi: 10.1002/eji.202149531.

Boettler, T., B. Csernalabics, H. Salie, H. Luxenburger, L. Wischer, E. Salimi Alizei, K. Zoldan, L. Krimmel, P. Bronsert, M. Schwabenland, M. Prinz, C. Mogler, C. Neumann-Haefelin, R. Thimme, M. Hofmann, and B. Bengsch. 2022. SARS-CoV-2 vaccination can elicit a CD8 T-cell dominant hepatitis. J Hepatol 77: 653-659. doi: 10.1016/j.jhep.2022.03.040.

Masuda, T., L. Amann, G. Monaco, R. Sankowski, O. Staszewski, M. Krueger, F. Del Gaudio, L. He, N. Paterson, E. Nent, F. Fernandez-Klett, A. Yamasaki, M. Frosch, M. Fliegauf, L. F. P. Bosch, H. Ulupinar, N. Hagemeyer, D. Schreiner, C. Dorrier, M. Tsuda, C. Grothe, A. Joutel, R. Daneman, C. Betsholtz, U. Lendahl, K. P. Knobeloch, T. Lammermann, J. Priller, K. Kierdorf, and M. Prinz. 2022. Specification of CNS macrophage subsets occurs postnatally in defined niches. Nature 604: 740-748. doi: 10.1038/s41586-022-04596-2.

Mossad, O., B. Batut, B. Yilmaz, N. Dokalis, C. Mezo, E. Nent, L. S. Nabavi, M. Mayer, F. J. M. Maron, J. M. Buescher, M. G. de Aguero, A. Szalay, T. Lammermann, A. J. Macpherson, S. C. Ganal-Vonarburg, R. Backofen, D. Erny, M. Prinz, and T. Blank. 2022. Gut microbiota drives age-related oxidative stress and mitochondrial damage in microglia via the metabolite N(6)-carboxymethyllysine. Nat Neurosci 25: 295-305

Erny, D., N. Dokalis, C. Mezo, O. Mossad, T. Blank, and M. Prinz. 2022. Flow-cytometry-based protocol to analyze respiratory chain function in mouse microglia. STAR Protoc 3: 101186.

d’Errico, P., S. Ziegler-Waldkirch, V. Aires, P. Hoffmann, C. Mezo, D. Erny, L. S. Monasor, S. Liebscher, V. M. Ravi, K. Joseph, O. Schnell, K. Kierdorf, O. Staszewski, S. Tahirovic, M. Prinz, and M. Meyer-Luehmann. 2022. Microglia contribute to the propagation of Abeta into unaffected brain tissue. Nat Neurosci 25: 20-25.

Schwabenland M, Salié H, Tanevski J, Killmer S, Lago MS, Schlaak AE, Mayer L, Matschke J, Püschel K, Fitzek A, Ondruschka B, Mei HE, Boettler T, Neumann-Haefelin C, Hofmann M, Breithaupt A, Genc N, Stadelmann C, Saez-Rodriguez J, Bronsert P, Knobeloch KP, Blank T, Thimme R, Glatzel M, Prinz M, Bengsch B. 2021. Deep spatial profiling of human COVID-19 brains reveals neuroinflammation with distinct microanatomical microglia-T-cell interactions. Immunity. 54(7):1594-1610.e11.

Prinz M, Masuda T, Wheeler MA, Quintana FJ. 2021. Microglia and Central Nervous System-Associated Macrophages-From Origin to Disease Modulation. Annu Rev Immunol. Feb 8. doi: 10.1146/annurev-immunol-093019-110159. Online ahead of print.

Wieghofer P, Hagemeyer N, Sankowski R, Schlecht A, Staszewski O, Amann L, Gruber M, Koch J, Hausmann A, Zhang P, Boneva S, Masuda T, Hilgendorf I, Goldmann T, Böttcher C, Priller J, Rossi FM, Lange C, Prinz M. 2021. Mapping the origin and fate of myeloid cells in distinct compartments of the eye by single-cell profiling.  EMBO J. 8:e105123. doi: 10.15252/embj.2020105123.

Chhatbar C, Prinz M. 2021. The roles of microglia in viral encephalitis: from sensome to therapeutic targeting.  Cell Mol Immunol. 18(2):250-258.

Berghoff SA, Spieth L, Sun T, Hosang L, Schlaphoff L, Depp C, Düking T, Winchenbach J, Neuber J, Ewers D, Scholz P, van der Meer F, Cantuti-Castelvetri L, Sasmita AO, Meschkat M, Ruhwedel T, Möbius W, Sankowski R, Prinz M, Huitinga I, Sereda MW, Odoardi F, Ischebeck T, Simons M, Stadelmann-Nessler C, Edgar JM, Nave KA, Saher G. 2020. Microglia facilitate repair of demyelinated lesions via post-squalene sterol synthesis. Nat Neurosci. 24(1):47-60. doi: 10.1038/s41593-020-00757-6.

Borst, K., and M. Prinz. 2020. Deciphering the heterogeneity of myeloid cells during neuroinflammation in the single cell era. Brain Pathol. doi: 10.1111/bpa.12910. Online ahead of print.

Bassett DS, Cullen KE, Eickhoff SB, Farah MJ, Goda Y, Haggard P, Hu H, Hurd YL, Josselyn SA, Khakh BS, Knoblich JA, Poirazi P, Poldrack RA, Prinz M, Roelfsema PR, Spires-Jones TL, Sur M, Ueda HR. 2020. Reflections on the past two decades of neuroscience. Nat Rev Neurosci. doi: 10.1038/s41583-020-0363-6. Online ahead of print.

Mezö C, Dokalis N, Mossad O, Staszewski O, Neuber J, Yilmaz B, Schnepf D, de Agüero MG, Ganal-Vonarburg SC, Macpherson AJ, Meyer-Luehmann M, Staeheli P, Blank T, Prinz M, Erny D. 2020. Different effects of constitutive and induced microbiota modulation on microglia in a mouse model of Alzheimer’s disease. Acta Neuropathol Commun. 8(1):119. doi: 10.1186/s40478-020-00988-5.

Masuda, T., L. Amann, R. Sankowski, O. Staszewski, M. Lenz, P. d Errico, N. Snaidero, M. J. Costa Jordao, C. Bottcher, K. Kierdorf, S. Jung, J. Priller, T. Misgeld, A. Vlachos, M. M. Luehmann, K. P. Knobeloch, and M. Prinz. 2020. Novel Hexb-based tools for studying microglia in the CNS. Nat Immunol 21: 802-815.

Amann, L., and M. Prinz. 2020. The origin, fate and function of macrophages in the peripheral nervous system – an update. Int Immunolpii. doi: 10.1093/intimm/dxaa030. [Epub ahead of print].

Ydens, E., L. Amann, B. Asselbergh, C. L. Scott, L. Martens, D. Sichien, O. Mossad, T. Blank, S. De Prijck, D. Low, T. Masuda, Y. Saeys, V. Timmerman, R. Stumm, F. Ginhoux, M.  Prinz, S. Janssens, and M. Guilliams. 2020. Profiling peripheral nerve macrophages reveals two macrophage subsets with distinct localization, transcriptome and response to injury. Nat Neurosci 23: 676-689.

Erny, D., and M. Prinz. 2020. How microbiota shape microglial phenotypes and epigenetics. Glia. doi: 10.1002/glia.23822. [Epub ahead of print]

Masuda, T., R. Sankowski, O. Staszewski, and M. Prinz. 2020. Microglia Heterogeneity in the Single-Cell Era. Cell Rep 30: 1271-1281.

Geirsdottir L, David E, Keren-Shaul H, Weiner A, Bohlen SC, Neuber J, Balic A, Giladi A, Sheban F, Dutertre CA, Pfeifle C, Peri F, Raffo-Romero A, Vizioli J, Matiasek K, Scheiwe C, Meckel S, Mätz-Rensing K, van der Meer F, Thormodsson FR, Stadelmann C, Zilkha N, Kimchi T, Ginhoux F, Ulitsky I, Erny D, Amit I, Prinz M. 2019.  Cross-Species Single-Cell Analysis Reveals Divergence of the Primate Microglia Program. Cell. 179:1609-1622.

R Mathew N, Vinnakota JM, Apostolova P, Erny D, Hamarsheh S, Andrieux G, Kim JS, Hanke K, Goldmann T, Chappell-Maor L, El-Khawanky N, Ihorst G, Schmidt D, Duyster J, Finke J, Blank T, Boerries M, Blazar BR, Jung S, Prinz M, Zeiser R. 2019. Graft-versus-host disease of the CNS is mediated by TNF upregulation in microglia. J Clin Invest. pii: 130272.

Sankowski R, Böttcher C, Masuda T, Geirsdottir L, Sagar, Sindram E, Seredenina T, Muhs A, Scheiwe C, Shah MJ, Heiland DH, Schnell O, Grün D, Priller J, Prinz M. 2019. Mapping microglia states in the human brain through the integration of high-dimensional techniques. Nat Neurosci. 22(12):2098-2110. doi: 10.1038/s41593-019-0532-y. Epub 2019 Nov 18.

Nikolaos Dokalis & Marco Prinz. 2019. Resolution of neuroinflammation: mechanisms and potential therapeutic option. Semin Immunopathol. 41(6):699-709. doi: 10.1007/s00281-019-00764-1. Epub 2019 Nov 8.

Kierdorf K, Masuda T, Jordão MJC, Prinz M. 2019. Macrophages at CNS interfaces: ontogeny and function in health and disease. Nat Rev Neurosci. 20(9):547-562. Review.

Masuda, T., R. Sankowski, O. Staszewski, C. Bottcher, L. Amann, Sagar, C. Scheiwe, S. Nessler, P. Kunz, G. van Loo, V. A. Coenen, P. C. Reinacher, A. Michel, U. Sure, R. Gold, D. Grun, J. Priller, C. Stadelmann, and M. Prinz. 2019. Spatial and temporal heterogeneity of mouse and human microglia at single-cell resolution. Nature 566: 388-392.

Fischer, J., C. Walter, A. Tonges, H. Aleth, M. J. C. Jordao, M. Leddin, V. Groning, T. Erdmann, G. Lenz, J. Roth, T. Vogl, M. Prinz, M. Dugas, I. D. Jacobsen, and F. Rosenbauer. 2019. Safeguard function of PU.1 shapes the inflammatory epigenome of neutrophils. Nat Immunol. 20(5):546-558.

Jordao, M. J. C., R. Sankowski, S. M. Brendecke, Sagar, G. Locatelli, Y. H. Tai, T. L. Tay, E. Schramm, S. Armbruster, N. Hagemeyer, O. Gross, D. Mai, O. Cicek, T. Falk, M. Kerschensteiner, D. Grun, and M. Prinz. 2019. Single-cell profiling identifies myeloid cell subsets with distinct fates during neuroinflammation. Science. 363(6425). pii:eaat7554.

Shemer, A., J. Grozovski, T. L. Tay, J. Tao, A. Volaski, P. Suss, A. Ardura-Fabregat, M. Gross-Vered, J. S. Kim, E. David, L. Chappell-Maor, L. Thielecke, C. K. Glass, K. Cornils, Prinz, and S. Jung. 2018. Engrafted parenchymal brain macrophages differ from microglia in transcriptome, chromatin landscape and response to challenge. Nat Commun 9: 5206.

Tay, T. L., Sagar, J. Dautzenberg, D. Grun, and Prinz. 2018. Unique microglia recovery population revealed by single-cell RNAseq following neurodegeneration. Acta Neuropathol Commun 6: 87.

Locatelli, G., D. Theodorou, A. Kendirli, M. J. C. Jordao, O. Staszewski, K. Phulphagar, L. Cantuti-Castelvetri, A. Dagkalis, A. Bessis, M. Simons, F. Meissner, Prinz, and M. Kerschensteiner. 2018. Mononuclear phagocytes locally specify and adapt their phenotype in a multiple sclerosis model. Nat Neurosci 21: 1196-1208.

Voet, S., C. Mc Guire, N. Hagemeyer, A. Martens, A. Schroeder, P. Wieghofer, C. Daems, O. Staszewski, L. V. Walle, M. J. C. Jordao, M. Sze, H. K. Vikkula, D. Demeestere, G. Van Imschoot, C. L. Scott, E. Hoste, A. Goncalves, M. Guilliams, S. Lippens, C. Libert, R. E. Vandenbroucke, K. W. Kim, S. Jung, Z. Callaerts-Vegh, P. Callaerts, J. de Wit, M. Lamkanfi, Prinz, and G. van Loo. 2018. A20 critically controls microglia activation and inhibits inflammasome-dependent neuroinflammation. Nat Commun 9: 2036.

Rothhammer, V., D. M. Borucki, E. C. Tjon, M. C. Takenaka, C. C. Chao, A. Ardura-Fabregat, K. A. de Lima, C. Gutierrez-Vazquez, P. Hewson, O. Staszewski, M. Blain, L. Healy, T. Neziraj, M. Borio, M. Wheeler, L. L. Dragin, D. A. Laplaud, J. Antel, J. I. Alvarez, Prinz, and F. J. Quintana. 2018. Microglial control of astrocytes in response to microbial metabolites. Nature 557: 724-728.

Mathew NR, Baumgartner F, Braun L, O’Sullivan D, Thomas S, Waterhouse M, Müller TA, Hanke K, Taromi S, Apostolova P, Illert AL, Melchinger W, Duquesne S, Schmitt-Graeff A, Osswald L, Yan KL, Weber A, Tugues S, Spath S, Pfeifer D, Follo M, Claus R, Lübbert M, Rummelt C, Bertz H, Wäsch R, Haag J, Schmidts A, Schultheiss M, Bettinger D, Thimme R, Ullrich E, Tanriver Y, Vuong GL, Arnold R, Hemmati P, Wolf D, Ditschkowski M, Jilg C, Wilhelm K, Leiber C, Gerull S, Halter J, Lengerke C, Pabst T, Schroeder T, Kobbe G, Rösler W, Doostkam S, Meckel S,Stabla K, Metzelder SK, Halbach S, Brummer T, Hu Z, Dengjel J, Hackanson B, Schmid C, Holtick U, Scheid C, Spyridonidis A, Stölzel F, Ordemann R, Müller LP, Sicre-de-Fontbrune F, Ihorst G, Kuball J, Ehlert JE, Feger D, Wagner EM, Cahn JY, Schnell J, Kuchenbauer F, Bunjes D, Chakraverty R, Richardson S, Gill S, Kröger N, Ayuk F, Vago L, Ciceri F, Müller AM, Kondo T, Teshima T, Klaeger S, Kuster B, Kim DDH, Weisdorf D, van der Velden W, Dörfel D, Bethge W, Hilgendorf I, Hochhaus A, Andrieux G, Börries M, Busch H, Magenau J, Reddy P, Labopin M, Antin JH, Henden AS, Hill GR, Kennedy GA, Bar M, Sarma A, McLornan D, Mufti G, Oran B, Rezvani K, Shah O, Negrin RS, Nagler A, Prinz M, Burchert A, Neubauer A, Beelen D, Mackensen A, von Bubnoff N, Herr W, Becher B, Socié G, Caligiuri MA, Ruggiero E, Bonini C, Häcker G, Duyster J, Finke J, Pearce E, Blazar BR, Zeiser R. Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells. Nat Med. 24: 282-291.

Datta, M., O. Staszewski, E. Raschi, M. Frosch, N. Hagemeyer, T. L. Tay, T. Blank, M. Kreutzfeldt, D. Merkler, S. Ziegler-Waldkirch, P. Matthias, M. Meyer-Luehmann, and Prinz. 2018. Histone Deacetylases 1 and 2 Regulate Microglia Function during Development, Homeostasis, and Neurodegeneration in a Context-Dependent Manner. Immunity 48: 514-529 e516.

Deczkowska, A., O. Matcovitch-Natan, A. Tsitsou-Kampeli, S. Ben-Hamo, R. Dvir-Szternfeld, A. Spinrad, O. Singer, E. David, D. R. Winter, L. K. Smith, A. Kertser, K. Baruch, N. Rosenzweig, A. Terem, Prinz, S. Villeda, A. Citri, I. Amit, and M. Schwartz. 2017. Mef2C restrains microglial inflammatory response and is lost in brain ageing in an IFN-I-dependent manner. Nat Commun 8: 717.

Quintana, F. J., and M. Prinz. 2017. A gut feeling about multiple sclerosis. Proc Natl Acad Sci U S A 114: 10528-10529

Mass, E., C. E. Jacome-Galarza, T. Blank, T. Lazarov, B. H. Durham, N. Ozkaya, A. Pastore, M. Schwabenland, Y. R. Chung, M. K. Rosenblum, Prinz, O. Abdel-Wahab, and F. Geissmann. 2017. A somatic mutation in erythro-myeloid progenitors causes neurodegenerative disease. Nature 549: 389-393.

Tay, T. L., D. Mai, J. Dautzenberg, F. Fernandez-Klett, G. Lin, Sagar, M. Datta, A. Drougard, T. Stempfl, A. Ardura-Fabregat, O. Staszewski, A. Margineanu, A. Sporbert, L. M. Steinmetz, J. A. Pospisilik, S. Jung, J. Priller, D. Grun, O. Ronneberger, and Prinz. 2017. A new fate mapping system reveals context-dependent random or clonal expansion of microglia. Nat Neurosci 20: 793-803.

Prinz, M., D. Erny, and N. Hagemeyer. 2017. Ontogeny and homeostasis of CNS myeloid cells. Nat Immunol 18: 385-392.

Prinz M, Priller J. 2017. The role of peripheral immune cells in the CNS in steady state and disease. Nat Neurosci. 20(2):136-144. Review.

Herrtwich L, Nanda I, Evangelou K, Nikolova T, Horn V, Sagar, Erny D, Stefanowski J, Rogell L, Klein C, Gharun K, Follo M, Seidl M, Kremer B, Münke N, Senges J, Fliegauf M, Aschman T, Pfeifer D, Sarrazin S, Sieweke MH, Wagner D, Dierks C, Haaf T, Ness T, Zaiss MM, Voll RE, Deshmukh SD, Prinz M, Goldmann T, Hölscher C, Hauser AE, Lopez-Contreras AJ, Grün D, Gorgoulis V, Diefenbach A, Henneke P, Triantafyllopoulou A. 2016. DNA Damage Signaling Instructs Polyploid Macrophage Fate in Granulomas. Cell. 167(5):1264-1280.

Peschke K, Achleitner M, Frenzel K, Gerbaulet A, Ada SR, Zeller N, Lienenklaus S, Lesche M, Poulet C, Naumann R, Dahl A, Ravens U, Günther C, Müller W, Knobeloch KP, Prinz M, Roers A, Behrendt R. 2016. Loss of Trex1 in Dendritic Cells Is Sufficient To Trigger Systemic Autoimmunity. J Immunol. 197:2157-2166.

Erny D, Hrabě de Angelis AL, Prinz M. 2017. Communicating systems in the body: how microbiota and microglia cooperate. Immunology. 150(1):7-15.

Hagemeyer N, Kierdorf K, Frenzel K, Xue J, Ringelhan M, Abdullah Z, Godin I, Wieghofer P, Costa Jordão MJ, Ulas T, Yorgancioglu G, Rosenbauer F, Knolle PA, Heikenwalder M, Schultze JL, Prinz M. 2016. Transcriptome-based profiling of yolk sac-derived macrophages reveals a role for Irf8 in macrophage maturation. EMBO J. 35:1730-1744.

Goldmann T, Wieghofer P, Jordão MJ, Prutek F, Hagemeyer N, Frenzel K, Amann L, Staszewski O, Kierdorf K, Krueger M, Locatelli G, Hochgerner H, Zeiser R, Epelman S, Geissmann F, Priller J, Rossi FM, Bechmann I, Kerschensteiner M, Linnarsson S, Jung S, Prinz M. 2016. Origin, fate and dynamics of macrophages at central nervous system interfaces. Nat Immunol. 17(7):797-805.

Brendecke SM, Prinz M. 2015. Do not judge a cell by its cover–diversity of CNS resident, adjoining and infiltrating myeloid cells in inflammation. Semin Immunopathol. 37(6):591-605.