Department for Medical Microbiology and Hygiene
Institute for Virology
Medical Center – University of Freiburg
Hermann Herder Str. 11
79104 Freiburg i. Brsg.
- +49 (0) 761/ 270 – 6579
- peter.staeheli@uniklinik-freiburg.de
- Homepage
Current position
Professor, Institute for Virology, Center for Microbiology and Hygiene, Medical Center – University of Freiburg
Academic training
| 1973 – 1977 | Studies of Microbiology and Biochemistry, ETH Zurich, Switzerland |
Scientific qualifications
| 1990 | Habilitation in Virology, University of Zurich, Switzerland (Mentor: Prof. Jean Lindenmann) |
| 1977 – 1981 | PhD Thesis, Institute for Microbiology, ETH Zurich, Switzerland (Supervisor: Prof. Ralf Hütter) |
Postgraduate Positions
| since 1990 | C3 Professor, Institute for Virology, Center for Microbiology and Hygiene, Medical Center – University of Freiburg |
| 1985 – 1987 | Postdoctorate, Research Institute of Scripps Clinic, La Jolla, CA, USA |
| 1983 – 1985 | Visiting Scientist at the Institute for Molecular Biology I, University of Zurich, Switzerland |
| 1982 | Internship in Molecular Biology as Visiting Scientist at E.I. du Pont de Nemours & Co., Wilmington, DE, USA |
| 1981 – 1985 | Postdoctorate, Institute for Immunology and Virology, University of Zurich, Switzerland |
Miscellaneous (Honors, Awards)
| 2008 | Milstein Award from the International Society for Interferon and Cytokine Research |
| 1992 | European Award for Interferon Research, Friends of the Hannover Medical School |
| 1992 | Award and Gold Medal, Foundation for Research in Science and the Humanities at the University of Zurich, Switzerland |
Publications based on CRC1160 funding
Graf L, Staeheli P. 2023. A human protein that holds bird flu viruses at bay. Nature. 619(7969):253-254. doi: 10.1038/d41586-023-01942-w.
Mezö C, Dokalis N, Mossad O, Staszewski O, Neuber J, Yilmaz B, Schnepf D, de Agüero MG, Ganal-Vonarburg SC, Macpherson AJ, Meyer-Luehmann M, Staeheli P, Blank T, Prinz M, Erny D. 2020. Different effects of constitutive and induced microbiota modulation on microglia in a mouse model of Alzheimer’s disease. Acta Neuropathol Commun. 8(1):119. doi: 10.1186/s40478-020-00988-5.
Gebhardt, A., V. Bergant, D. Schnepf, M. Moser, A. Meiler, D. Togbe, C. Mackowiak, L. S. Reinert, S. R. Paludan, B. Ryffel, A. Stukalov, P. Staeheli, and A. Pichlmair. 2019. The alternative cap-binding complex is required for antiviral defense in vivo. PLoS Pathog 15: e1008155.
Lee, S., A. Ishitsuka, M. Noguchi, M. Hirohama, Y. Fujiyasu, P. P. Petric, Schwemmle, P. Staeheli, K. Nagata, and A. Kawaguchi. 2019. Influenza restriction factor MxA functions as inflammasome sensor in the respiratory epithelium. Sci Immunol 4:eaau4643. doi: 10.1126/sciimmunol.aau4643
Bradley KC, Finsterbusch K, Schnepf D, Crotta S, Llorian M, Davidson S, Fuchs SY, Staeheli P, Wack A. 2019. Microbiota-Driven Tonic Interferon Signals in Lung Stromal Cells Protect from Influenza Virus Infection. Cell Rep. 28(1):245-256.
Holze C, Michaudel C, Mackowiak C, Haas DA, Benda C, Hubel P, Pennemann FL, Schnepf D, Wettmarshausen J, Braun M, Leung DW, Amarasinghe GK, Perocchi F, Staeheli P, Ryffel B, Pichlmair A. 2018. Oxeiptosis, a ROS-induced caspase-independent apoptosis-like cell-death pathway. Nat Immunol. 19(2):130-140. Epub 2017 Dec 18.
Deeg CM, Hassan E, Mutz P, Rheinemann L, Götz V, Magar L, Schilling M, Kallfass C, Nürnberger C, Soubies S, Kochs G, Haller O, Schwemmle M, Staeheli P. 2017. In vivo evasion of MxA by avian influenza viruses requires human signature in the viral nucleoprotein. J Exp Med. 214(5):1239-1248.
Pillai PS, Molony RD, Martinod K, Dong H, Pang IK, Tal MC, Solis AG, Bielecki P, Mohanty S, Trentalange M, Homer RJ, Flavell RA, Wagner DD, Montgomery RR, Shaw AC, Staeheli P, Iwasaki A. 2016. Mx1 reveals innate pathways to antiviral resistance and lethal influenza disease. Science. 352:463-466.
