Principal Investigator

Center for Medicine
Department of Medicine II
Medical Center – University of Freiburg

Hugstetter Str. 55
79106 Freiburg i. Brsg.

Current position

Group leader, Department of Medicine II (Gastroenterology, Hepatology, Endocrinology, and Infectious Diseases), Center for Medicine, Medical Center – University of Freiburg

Academic training

2004 - 2009 Study of Biochemical Engineering and Biotechnology, Indian Institute of Technology, Delhi, India

Scientific qualifications

2010 - 2014 Dissertation in Developmental Biology, University of Freiburg (Supervisor: Prof. Dr. Martin Scaal)

Postgraduate Positions

since 2020 Group leader, Department of Medicine II, Medical Center – University of Freiburg
2015 - 2020 Postdoctorate, Max Planck Institute of Immunobiology and Epigenetics, Freiburg
2015 Postdoctorate, Department of Developmental and Stem Cell Biology, Pasteur Institute, Paris, France 

link to all publications from Sagar: ORCID ID

Publications based on CRC1160 funding

Heim K, Sagar, Sogukpinar Ö, Llewellyn-Lacey S, Price DA, Emmerich F, Kraft ARM, Cornberg M, Kielbassa S, Knolle P, Wohlleber D, Bengsch B, Boettler T, Neumann-Haefelin C, Thimme R, Hofmann M. 2024. Attenuated effector T cells are linked to control of chronic HBV infection. Nat Immunol. 25(9):1650-1662. doi: 10.1038/s41590-024-01928-4.

Arnold F, Kupferschmid L, Weissenborn P, Heldmann L, Hummel JF, Zareba P, Sagar, Rogg M, Schell C, Tanriver Y. 2024. Tissue-resident memory T cells break tolerance to renal autoantigens and orchestrate immune-mediated nephritis. Cell Mol Immunol. Jul 3. doi: 10.1038/s41423-024-01197-z.

Herr LA, Fiala GJ, Sagar, Schaffer AM, Hummel JF, Zintchenko M, Raute K, Velasco Cárdenas RM, Heizmann B, Ebert K, Fehrenbach K, Janowska I, Chan S, Tanriver Y, Minguet S, Schamel WW. 2024. Kidins220 and Aiolos promote thymic iNKT cell development by reducing TCR signals. Sci Adv. 10(11):eadj2802. doi: 10.1126/sciadv.adj2802.

du Halgouet A, Bruder K, Peltokangas N, Darbois A, Obwegs D, Salou M, Thimme R, Hofmann M, Lantz O, Sagar. 2024. Multimodal profiling reveals site-specific adaptation and tissue residency hallmarks of γδ T cells across organs in mice. Nat Immunol. 2024. 343-356. doi: 10.1038/s41590-023-01710-y.

du Halgouet A, Bruder K, Peltokangas N, Darbois A, Obwegs D, Salou M, Thimme R, Hofmann M, Lantz O, Sagar. 2024. Multimodal profiling reveals site-specific adaptation and tissue residency hallmarks of γδ T cells across organs in mice. Nat Immunol. 2024 Jan 4. doi: 10.1038/s41590-023-01710-y.

Sagar. 2024. Unraveling the secrets of γδ T cells with single-cell biology. J Leukoc Biol Vol. 115 Issue 1 Pages 47-56 DOI: 10.1093/jleuko/qiad131