Publications

Globig AM, Mayer LS, Heeg M, Andrieux G, Ku M, Otto-Mora P, Hipp A, Zoldan K, Pattekar A, Rana N, Schell C, Boerries M, Hofmann M, Neumann-Haefelin C, Kuellmer A, Schmidt A, Boettler T, Tomov V, Thimme R, Hasselblatt P, Bengsch B. Gastroenterology. 2022. Exhaustion of CD39-expressing CD8+ T cells in Crohn’s disease is linked to clinical outcome. First published: 2022 Jun 20:S0016-5085(22)00663-1. doi: 10.1053/j.gastro.2022.06.045. Online ahead of print.

Saghafi, S., F. Zandieh, M. R. Fazlollahi, C. Glocker, N. Frede, M. Buchta, L. Yang, A. H. Mahmoudi, M. Houshmand, Z. Pourpak, B. Grimbacher, and M. Moin. 2022. Confirmation of Hyperimmunoglobulin E Syndrome in Two Patients with an Ocular Problem: Detection of Two New DOCK8 Mutations. Iran J Allergy Asthma Immunol 21: 355-363. doi: 10.18502/ijaai.v21i3.9809.

Czech M, Zeiser R, Toubai T. Front Immunol. 2022. Editorial on Translational Research in Graft-Versus-Host Disease (GVHD) and Graft-Versus-Tumor (GVT) Effect After Allogeneic Hematopoietic Cell Transplantation. First published: 2022 Jun 8;13:948720. doi: 10.3389/fimmu.2022.948720. eCollection 2022. PMID: 35757690 Free PMC article.

Czech M, Zeiser R, Toubai T. 2022. Editorial on Translational Research in Graft-Versus-Host Disease (GVHD) and Graft-Versus-Tumor (GVT) Effect After Allogeneic Hematopoietic Cell Transplantation. Front Immunol. 2022 Jun 8;13:948720. doi: 10.3389/fimmu.2022.948720.

Bexte, T., J. Alzubi, L. M. Reindl, P. Wendel, R. Schubert, E. Salzmann-Manrique, I. von Metzler, T. Cathomen, and E. Ullrich. 2022. CRISPR-Cas9 based gene editing of the immune checkpoint NKG2A enhances NK cell mediated cytotoxicity against multiple myeloma. Oncoimmunology 11: 2081415. doi: 10.1080/2162402X.2022.2081415.

Kemming, J., S. Gundlach, M. Panning, D. Huzly, J. Huang, M. Lutgehetmann, S. Pischke, J. Schulze Zur Wiesch, F. Emmerich, S. Llewellyn-Lacey, D. A. Price, Y. Tanriver, K. Warnatz, T. Boettler, R. Thimme, M. Hofmann, N. Fischer, and C. Neumann-Haefelin. 2022. Mechanisms of CD8+ T-cell failure in chronic hepatitis E virus infection. J Hepatol 77: 978-990. doi: 10.1016/j.jhep.2022.05.019.

Gross, M., C. Speckmann, A. May, T. Gajardo-Carrasco, K. Wustrau, S. L. Maier, M. Panning, D. Huzly, A. Agaimy, Y. T. Bryceson, S. Choo, C. W. Chow, G. Duckers, A. Fasth, S. Fraitag, K. Grawe, S. Haxelmans, D. Holzinger, O. Hudowenz, J. M. Hubschen, C. Khurana, K. Kienle, R. Klifa, K. Korn, H. Kutzner, T. Lammermann, S. Ledig, D. Lipsker, M. Meeths, N. Naumann-Bartsch, J. Rascon, A. Schanzer, M. Seidl, B. Tesi, C. Vauloup-Fellous, B. Vollmer-Kary, K. Warnatz, C. Wehr, B. Neven, P. Vargas, F. E. Sepulveda, K. Lehmberg, A. Schmitt-Graeff, and S. Ehl. 2022. Rubella vaccine-induced granulomas are a novel phenotype with incomplete penetrance of genetic defects in cytotoxicity. J Allergy Clin Immunol 149: 388-399.e4. doi: 10.1016/j.jaci.2021.05.007.

Friedrich M, Hahn M, Michel J, Sankowski R, Kilian M, Kehl N, Günter M, Bunse T, Pusch S, von Deimling A, Wick W, Autenrieth SE, Prinz M, Platten M, Bunse L. Neuro Oncol. 2022. Dysfunctional dendritic cells limit antigen-specific T cell response in glioma. First Published: 2022 May 24:noac138. doi: 10.1093/neuonc/noac138.

Klocperk A, Friedmann D, Schlaak AE, Unger S, Parackova Z, Goldacker S, Sediva A, Bengsch B, Warnatz K. 2022. Distinct CD8 T Cell Populations with Differential Exhaustion Profiles Associate with Secondary Complications in Common Variable Immunodeficiency. J Clin Immunol, First published: 2022 May 19. doi: 10.1007/s10875-022-01291-9.

Holzen, L., J. Mitschke, C. Schonichen, M. E. Hess, S. Ehrenfeld, M. Boerries, C. Miething, T. Brummer, and T. Reinheckel. 2022. RNA interference screens discover proteases as synthetic lethal partners of PI3K inhibition in breast cancer cells. Theranostics 12: 4348-4373. doi: 10.7150/thno.68299.

Hölzen L, Mitschke J, Schönichen C, Hess ME, Ehrenfeld S, Boerries M, Miething C, Brummer T, Reinheckel T. 2022. RNA interference screens discover proteases as synthetic lethal partners of PI3K inhibition in breast cancer cells. Theranostics. 12(9):4348-4373. doi: 10.7150/thno.68299.

Kolter J, Henneke P, Groß O, Kierdorf K, Prinz M, Graf L, Schwemmle M. 2022. Paradoxical immunodeficiencies-When failures of innate immunity cause immunopathology. Eur J Immunol. First published: 2022 May 12. doi: 10.1002/eji.202149531.

Devane J, Ott E, Olinger EG, Epting D, Decker E, Friedrich A, Bachmann N, Renschler G, Eisenberger T, Briem-Richter A, Grabhorn EF, Powell L, Wilson IJ, Rice SJ, Miles CG, Wood K; Genomics England Research Consortium, Trivedi P, Hirschfield G, Pietrobattista A, Wohler E, Mezina A, Sobreira N, Agolini E, Maggiore G, Dahmer-Heath M, Yilmaz A, Boerries M, Metzger P, Schell C, Grünewald I, Konrad M, König J, Schlevogt B, Sayer JA, Bergmann C. Am J Hum Genet. 2022.  Progressive liver, kidney, and heart degeneration in children and adults affected by TULP3 mutations. Published 2022 May 5;109(5):928-943. doi: 10.1016/j.ajhg.2022.03.015. Epub 2022 Apr 8. PMID: 35397207

Lang-Meli, J., H. Luxenburger, K. Wild, V. Karl, V. Oberhardt, E. Salimi Alizei, A. Graeser, M. Reinscheid, N. Roehlen, D. B. Reeg, S. Giese, K. Ciminski, V. Gotz, D. August, S. Rieg, C. F. Waller, T. Wengenmayer, D. Staudacher, D. Huzly, B. Bengsch, G. Kochs, M. Schwemmle, F. Emmerich, T. Boettler, R. Thimme, M. Hofmann, and C. Neumann-Haefelin. 2022. SARS-CoV-2-specific T-cell epitope repertoire in convalescent and mRNA-vaccinated individuals. Nat Microbiol 7: 675-679. doi: 10.1038/s41564-022-01106-y.

Wan, R., M. Schieck, A. Caballero-Oteyza, W. Hofmann, A. V. Cochino, A. Shcherbina, R. Sherkat, C. Wache-Mainier, A. Fernandez, M. Sultan, T. Illig, B. Grimbacher, M. Proietti, and D. Steinemann. 2022. Copy Number Analysis in a Large Cohort Suggestive of Inborn Errors of Immunity Indicates a Wide Spectrum of Relevant Chromosomal Losses and Gains. J Clin Immunol 42: 1083-1092. doi: 10.1007/s10875-022-01276-8.

Boettler, T., B. Csernalabics, H. Salie, H. Luxenburger, L. Wischer, E. Salimi Alizei, K. Zoldan, L. Krimmel, P. Bronsert, M. Schwabenland, M. Prinz, C. Mogler, C. Neumann-Haefelin, R. Thimme, M. Hofmann, and B. Bengsch. 2022. SARS-CoV-2 vaccination can elicit a CD8 T-cell dominant hepatitis. J Hepatol 77: 653-659. doi: 10.1016/j.jhep.2022.03.040.