Publications

Gross, M., C. Speckmann, A. May, T. Gajardo-Carrasco, K. Wustrau, S. L. Maier, M. Panning, D. Huzly, A. Agaimy, Y. T. Bryceson, S. Choo, C. W. Chow, G. Duckers, A. Fasth, S. Fraitag, K. Grawe, S. Haxelmans, D. Holzinger, O. Hudowenz, J. M. Hubschen, C. Khurana, K. Kienle, R. Klifa, K. Korn, H. Kutzner, T. Lammermann, S. Ledig, D. Lipsker, M. Meeths, N. Naumann-Bartsch, J. Rascon, A. Schanzer, M. Seidl, B. Tesi, C. Vauloup-Fellous, B. Vollmer-Kary, K. Warnatz, C. Wehr, B. Neven, P. Vargas, F. E. Sepulveda, K. Lehmberg, A. Schmitt-Graeff, and S. Ehl. 2022. Rubella vaccine-induced granulomas are a novel phenotype with incomplete penetrance of genetic defects in cytotoxicity. J Allergy Clin Immunol 149: 388-399.e4. doi: 10.1016/j.jaci.2021.05.007.

Friedrich M, Hahn M, Michel J, Sankowski R, Kilian M, Kehl N, Günter M, Bunse T, Pusch S, von Deimling A, Wick W, Autenrieth SE, Prinz M, Platten M, Bunse L. Neuro Oncol. 2022. Dysfunctional dendritic cells limit antigen-specific T cell response in glioma. First Published: 2022 May 24:noac138. doi: 10.1093/neuonc/noac138.

Klocperk A, Friedmann D, Schlaak AE, Unger S, Parackova Z, Goldacker S, Sediva A, Bengsch B, Warnatz K. 2022. Distinct CD8 T Cell Populations with Differential Exhaustion Profiles Associate with Secondary Complications in Common Variable Immunodeficiency. J Clin Immunol, First published: 2022 May 19. doi: 10.1007/s10875-022-01291-9.

Holzen, L., J. Mitschke, C. Schonichen, M. E. Hess, S. Ehrenfeld, M. Boerries, C. Miething, T. Brummer, and T. Reinheckel. 2022. RNA interference screens discover proteases as synthetic lethal partners of PI3K inhibition in breast cancer cells. Theranostics 12: 4348-4373. doi: 10.7150/thno.68299.

Hölzen L, Mitschke J, Schönichen C, Hess ME, Ehrenfeld S, Boerries M, Miething C, Brummer T, Reinheckel T. 2022. RNA interference screens discover proteases as synthetic lethal partners of PI3K inhibition in breast cancer cells. Theranostics. 12(9):4348-4373. doi: 10.7150/thno.68299.

Kolter J, Henneke P, Groß O, Kierdorf K, Prinz M, Graf L, Schwemmle M. 2022. Paradoxical immunodeficiencies-When failures of innate immunity cause immunopathology. Eur J Immunol. First published: 2022 May 12. doi: 10.1002/eji.202149531.

Devane J, Ott E, Olinger EG, Epting D, Decker E, Friedrich A, Bachmann N, Renschler G, Eisenberger T, Briem-Richter A, Grabhorn EF, Powell L, Wilson IJ, Rice SJ, Miles CG, Wood K; Genomics England Research Consortium, Trivedi P, Hirschfield G, Pietrobattista A, Wohler E, Mezina A, Sobreira N, Agolini E, Maggiore G, Dahmer-Heath M, Yilmaz A, Boerries M, Metzger P, Schell C, Grünewald I, Konrad M, König J, Schlevogt B, Sayer JA, Bergmann C. Am J Hum Genet. 2022.  Progressive liver, kidney, and heart degeneration in children and adults affected by TULP3 mutations. Published 2022 May 5;109(5):928-943. doi: 10.1016/j.ajhg.2022.03.015. Epub 2022 Apr 8. PMID: 35397207

Lang-Meli, J., H. Luxenburger, K. Wild, V. Karl, V. Oberhardt, E. Salimi Alizei, A. Graeser, M. Reinscheid, N. Roehlen, D. B. Reeg, S. Giese, K. Ciminski, V. Gotz, D. August, S. Rieg, C. F. Waller, T. Wengenmayer, D. Staudacher, D. Huzly, B. Bengsch, G. Kochs, M. Schwemmle, F. Emmerich, T. Boettler, R. Thimme, M. Hofmann, and C. Neumann-Haefelin. 2022. SARS-CoV-2-specific T-cell epitope repertoire in convalescent and mRNA-vaccinated individuals. Nat Microbiol 7: 675-679. doi: 10.1038/s41564-022-01106-y.

Wan, R., M. Schieck, A. Caballero-Oteyza, W. Hofmann, A. V. Cochino, A. Shcherbina, R. Sherkat, C. Wache-Mainier, A. Fernandez, M. Sultan, T. Illig, B. Grimbacher, M. Proietti, and D. Steinemann. 2022. Copy Number Analysis in a Large Cohort Suggestive of Inborn Errors of Immunity Indicates a Wide Spectrum of Relevant Chromosomal Losses and Gains. J Clin Immunol 42: 1083-1092. doi: 10.1007/s10875-022-01276-8.

Boettler, T., B. Csernalabics, H. Salie, H. Luxenburger, L. Wischer, E. Salimi Alizei, K. Zoldan, L. Krimmel, P. Bronsert, M. Schwabenland, M. Prinz, C. Mogler, C. Neumann-Haefelin, R. Thimme, M. Hofmann, and B. Bengsch. 2022. SARS-CoV-2 vaccination can elicit a CD8 T-cell dominant hepatitis. J Hepatol 77: 653-659. doi: 10.1016/j.jhep.2022.03.040.

Masuda, T., L. Amann, G. Monaco, R. Sankowski, O. Staszewski, M. Krueger, F. Del Gaudio, L. He, N. Paterson, E. Nent, F. Fernandez-Klett, A. Yamasaki, M. Frosch, M. Fliegauf, L. F. P. Bosch, H. Ulupinar, N. Hagemeyer, D. Schreiner, C. Dorrier, M. Tsuda, C. Grothe, A. Joutel, R. Daneman, C. Betsholtz, U. Lendahl, K. P. Knobeloch, T. Lammermann, J. Priller, K. Kierdorf, and M. Prinz. 2022. Specification of CNS macrophage subsets occurs postnatally in defined niches. Nature 604: 740-748. doi: 10.1038/s41586-022-04596-2.

Susana Minguet, Alexander Nyström, Dimitra Kiritsi, Marta Rizzi. 2022. Inborn errors of immunity and immunodeficiencies: Antibody-mediated pathology and autoimmunity as a consequence of impaired immune reactions. Eur J Immunol, First published: 20 April 2022; doi.org/10.1002/eji.202149529

Schauer F, Nyström A, Kunz M, Hübner S, Scholl S, Athanasiou I, Alter S, Fischer J, Has C, Kiritsi D. 2022. Case Report: Diagnostic and Therapeutic Challenges in Severe Mechanobullous Epidermolysis Bullosa Acquisita. Front Immunol. 13:883967.  doi: 10.3389/fimmu.2022.883967.

Haimovici A, Höfer C, Badr MT, Bavafaye Haghighi E, Amer T, Boerries M, Bronsert P, Glavynskyi I, Fanfone D, Ichim G, Thilmany N, Weber A, Brummer T, Spohr C, Öllinger R, Janssen KP, Rad R, Häcker G. 2022. Spontaneous activity of the mitochondrial apoptosis pathway drives chromosomal defects, the appearance of micronuclei and cancer metastasis through the Caspase-Activated DNAse. Cell Death Dis. 2022 13(4):315. doi: 10.1038/s41419-022-04768-y.

Unberath, P., L. Mahlmeister, N. Reimer, H. Busch, M. Boerries, and J. Christoph. 2022. Searching of Clinical Trials Made Easier in cBioPortal Using Patients’ Genetic and Clinical Profiles. Appl Clin Inform 13: 363-369. doi: 10.1055/s-0042-1743560.

Wanner, N., G. Andrieux, I. M. P. Badia, C. Edler, S. Pfefferle, M. T. Lindenmeyer, C. Schmidt-Lauber, J. Czogalla, M. N. Wong, Y. Okabayashi, F. Braun, M. Lutgehetmann, E. Meister, S. Lu, M. L. M. Noriega, T. Gunther, A. Grundhoff, N. Fischer, H. Brauninger, D. Lindner, D. Westermann, F. Haas, K. Roedl, S. Kluge, M. M. Addo, S. Huber, A. W. Lohse, J. Reiser, B. Ondruschka, J. P. Sperhake, J. Saez-Rodriguez, M. Boerries, S. S. Hayek, M. Aepfelbacher, P. Scaturro, V. G. Puelles, and T. B. Huber. 2022. Molecular consequences of SARS-CoV-2 liver tropism. Nat Metab 4: 310-319. doi: 10.1038/s42255-022-00552-6.