Publications

Schutze, K., M. Gross, K. Cornils, K. Wustrau, S. Schneppenheim, H. Lenhartz, G. C. Korenke, G. Janka, S. Ledig, I. Muller, S. Ehl, and K. Lehmberg. 2022. MAP kinase activating death domain deficiency is a novel cause of impaired lymphocyte cytotoxicity. Blood Adv. pii: 486738. doi: 10.1182/bloodadvances.2022008195.

Krausz, M., A. Uhlmann, I. C. Rump, G. Ihorst, S. Goldacker, G. Sogkas, S. Posadas-Cantera, R. Schmidt, M. Feisst, L. Alsina, I. Dybedal, M. Recher, Warnatz, and B. Grimbacher. 2022. The ABACHAI clinical trial protocol: Safety and efficacy of abatacept (s.c.) in patients with CTLA-4 insufficiency or LRBA deficiency: A non controlled phase 2 clinical trial. Contemp Clin Trials Commun 30: 101008. doi: 10.1016/j.conctc.2022.101008.

Cook, J., and M. Prinz. 2022. Regulation of microglial physiology by the microbiota. Gut Microbes 14: 2125739. doi: 10.1080/19490976.2022.2125739.

Beer, J., S. Crotta, A. Breithaupt, A. Ohnemus, J. Becker, B. Sachs, L. Kern, M. Llorian, N. Ebert, F. Labroussaa, T. T. Nhu Thao, B. S. Trueeb, J. Jores, V. Thiel, M. Beer, J. Fuchs, G. Kochs, A. Wack, M. Schwemmle, and D. Schnepf. 2022. Impaired immune response drives age-dependent severity of COVID-19. J Exp Med 219: pii: 213485. doi: 10.1084/jem.20220621.

Chakraborty, S., G. Andrieux, P. Kastl, L. Adlung, S. Altamura, M. E. Boehm, L. E. Schwarzmuller, Y. Abdullah, M. C. Wagner, B. Helm, H. J. Grone, W. D. Lehmann, M. Boerries, H. Busch, M. U. Muckenthaler, M. Schilling, and U. Klingmuller. 2022. Erythropoietin-driven dynamic proteome adaptations during erythropoiesis prevent iron overload in the developing embryo. Cell Rep 40: 111360. doi: 10.1016/j.celrep.2022.111360.

Melendez, A. V., R. M. Velasco Cardenas, S. Lagies, J. Strietz, L. Siukstaite, O. S. Thomas, J. Tomisch, W. Weber, B. Kammerer, W. Romer, and S. Minguet. 2022. Novel lectin-based chimeric antigen receptors target Gb3-positive tumour cells. Cell Mol Life Sci 79: 513. doi: 10.1007/s00018-022-04524-7.

Ho, J., D. Schmidt, T. Lowinus, J. Ryoo, E. P. Dopfer, N. Gonzalo Nunez, S. Costa-Pereira, C. Toffalori, M. Punta, V. Fetsch, T. Wertheimer, M. C. Rittmann, L. M. Braun, M. Follo, C. Briere, J. M. Vinnakota, M. Langenbach, F. Koppers, K. Shoumariyeh, H. Engel, T. Ruckert, M. Marklin, S. Holzmayer, A. L. Illert, F. Magon, G. Andrieux, S. Duquesne, D. Pfeifer, J. Staniek, M. Rizzi, C. Miething, N. Kohler, J. Duyster, H. D. Menssen, M. Boerries, J. M. Buescher, N. Cabezas-Wallscheid, B. R. Blazar, P. Apostolova, L. Vago, E. L. Pearce, B. Becher, and R. Zeiser. 2022. Targeting MDM2 enhances antileukemia immunity after allogeneic transplantation via MHC-II and TRAIL-R1/2 upregulation. Blood 140: 1167-1181. doi: 10.1182/blood.2022016082.

Braig, D., A. Runkel, A. E. Eisenhardt, A. Schmid, J. Zeller, T. Pauli, U. Lausch, J. Wehrle, P. Bronsert, M. Jung, J. Kiefer, M. Boerries, and S. U. Eisenhardt. 2022. Individualized Mini-Panel Sequencing of ctDNA Allows Tumor Monitoring in Complex Karyotype Sarcomas. Int J Mol Sci 23: pii: ijms231810215. doi: 10.3390/ijms231810215.

Schultz, A., M. Schnurra, A. El-Bizri, N. M. Woessner, S. Hartmann, R. Hartig, S. Minguet, B. Schraven, and L. Simeoni. 2022. A Cysteine Residue within the Kinase Domain of Zap70 Regulates Lck Activity and Proximal TCR Signaling. Cells 11. pii: cells11172723. doi: 10.3390/cells11172723.

Fliegauf, M., M. Kinnunen, S. Posadas-Cantera, N. Camacho-Ordonez, H. Abolhassani, L. Alsina, F. Atschekzei, D. J. Bogaert, S. O. Burns, J. A. Church, G. Duckers, A. F. Freeman, L. Hammarstrom, L. G. Hanitsch, T. Kerre, R. Kobbe, S. O. Sharapova, K. Siepermann, C. Speckmann, S. Steiner, N. Verma, J. E. Walter, E. Westermann-Clark, S. Goldacker, K. Warnatz, M. Varjosalo, and B. Grimbacher. 2022. Detrimental NFKB1 missense variants affecting the Rel-homology domain of p105/p50. Front Immunol 13: 965326. doi: 10.3389/fimmu.2022.965326.

Aktories, P., P. Petry, P. Glatz, G. Andrieux, A. Oschwald, H. Botterer, O. Gorka, D. Erny, M. Boerries, P. Henneke, O. Gross, M. Prinz, and K. Kierdorf. 2022. An improved organotypic cell culture system to study tissue-resident macrophages ex vivo. Cell Rep Methods 2: 100260. doi: 10.1016/j.crmeth.2022.100260.

Ramirez, N., S. Posadas-Cantera, N. Langer, A. C. G. de Oteyza, M. Proietti, B. Keller, F. Zhao, V. Gernedl, M. Pecoraro, H. Eibel, K. Warnatz, E. Ballestar, R. Geiger, C. Bossen, and B. Grimbacher. 2022. Multi-omics analysis of naive B cells of patients harboring the C104R mutation in TACI. Front Immunol 13: 938240. doi: 10.3389/fimmu.2022.938240.

Ehl, S., and R. Thimme. 2022. Immune-mediated pathology as a consequence of impaired immune reactions: the IMPATH paradox. Eur J Immunol 52: 1386-1389. doi: 10.1002/eji.202250069.

Karlowitz, R., M. L. Stanifer, J. Roedig, G. Andrieux, D. Bojkova, M. Bechtel, S. Smith, L. Kowald, R. Schubert, M. Boerries, J. Cinatl, Jr., S. Boulant, and S. J. L. van Wijk. 2022. USP22 controls type III interferon signaling and SARS-CoV-2 infection through activation of STING. Cell Death Dis 13: 684. doi: 10.1038/s41419-022-05124-w.

Lehr, S., F. Meiss, D. Kiritsi, and L. Tsakiris. 2022. Small-Vessel Vasculitis After ST-Segment Elevation Myocardial Infarction: Clopidogrel or Amiodarone? JACC Case Rep 4: 967-971. doi: 10.1016/j.jaccas.2022.05.008.

Lehr, S., F. Felber, I. Tantcheva-Poor, C. Kessler, R. Eming, A. Nystrom, M. Rizzi, and D. Kiritsi. 2022. Occurrence of autoantibodies against skin proteins in patients with hereditary epidermolysis bullosa predisposes to development of autoimmune blistering disease. Front Immunol 13: 945176. doi: 10.3389/fimmu.2022.945176.