Publications

Andrieux G, Chakraborty S, Das T, Boerries M. 2020. Alteration of Proteotranscriptomic Landscape Reveals the Transcriptional Regulatory Circuits Controlling Key-Signaling Pathways and Metabolic Reprogramming During Tumor Evolution.  Front Cell Dev Biol. 8:586479. doi: 10.3389/fcell.2020.586479.

Ohishi Y, Ammann S, Ziaee V, Strege K, Groß M, Amos CV, Shahrooei M, Ashournia P, Razaghian A, Griffiths GM, Ehl S, Fukuda M, Parvaneh N. 2020. Griscelli Syndrome Type 2 Sine Albinism: Unraveling Differential RAB27A Effector Engagement.  Front Immunol. 11:612977. doi: 10.3389/fimmu.2020.612977.

Swann JB, Nusser A, Morimoto R, Nagakubo D, Boehm T. 2020. Retracing the evolutionary emergence of thymopoiesis. Sci Adv. 6(48):eabd9585. doi: 10.1126/sciadv.abd9585.

Schaffer AM, Minguet S. 2020. Caveolin-1, tetraspanin CD81 and flotillins in lymphocyte cell membrane organization, signaling and immunopathology. Biochem Soc Trans. BST20190387. doi: 10.1042/BST20190387. Online ahead of print.

Arnold F, Westermann L, Rieg S, Neumann-Haefelin E, Biever PM, Walz G, Kalbhenn J, Tanriver Y. 2020. Comparison of different anticoagulation strategies for renal replacement therapy in critically ill patients with COVID-19: a cohort study.  BMC Nephrol. 21(1):486. doi: 10.1186/s12882-020-02150-8.

Vazquez-Armendariz, A. I., M. Heiner, E. El Agha, I. Salwig, A. Hoek, M. C. Hessler, I. Shalashova, A. Shrestha, G. Carraro, J. P. Mengel, A. Gunther, R. E. Morty, I. Vadasz, M. Schwemmle, W. Kummer, T. Hain, A. Goesmann, S. Bellusci, W. Seeger, T. Braun, and Herold. 2020. Multilineage murine stem cells generate complex organoids to model distal lung development and disease. EMBO J: e103476.

Hamarsheh, S., O. Gross, T. Brummer, and R. Zeiser. 2020. Immune modulatory effects of oncogenic KRAS in cancer. Nat Commun 11: 5439.

Uhl, F. M., S. Chen, D. O’Sullivan, J. Edwards-Hicks, G. Richter, E. Haring, G. Andrieux, S. Halbach, P. Apostolova, J. Buscher, S. Duquesne, W. Melchinger, B. Sauer, K. Shoumariyeh, A. Schmitt-Graeff, M. Kreutz, M. Lubbert, J. Duyster, T. Brummer, M. Boerries, T. Madl, B. R. Blazar, O. Gross, E. L. Pearce, and R. Zeiser. 2020. Metabolic reprogramming of donor T cells enhances graft-versus-leukemia effects in mice and humans. Sci Transl Med 12:eabb8969. doi: 10.1126/scitranslmed.abb8969.

Akasaka E, Kleiser S, Sengle G, Bruckner-Tuderman L, Nyström A. 2020. Diversity of Mechanisms Underlying Latent TGF-β Activation in Recessive Dystrophic Epidermolysis Bullosa. J Invest Dermatol. S0022-202X(20)32357-5. doi: 10.1016/j.jid.2020.10.024. Online ahead of print.

Heim, K., B. Binder, Sagar, D. Wieland, N. Hensel, S. Llewellyn-Lacey, E. Gostick, D. A. Price, F. Emmerich, H. Vingerhoet, A. R. M. Kraft, M. Cornberg, T. Boettler, C. Neumann-Haefelin, D. Zehn, B. Bengsch, M. Hofmann, and R. Thimme. 2020. TOX defines the degree of CD8+ T cell dysfunction in distinct phases of chronic HBV infection. Gut. doi: 10.1136/gutjnl-2020-322404. Online ahead of print.

Basho K, Zoldan K, Schultheiss M, Bettinger D, Globig AM, Bengsch B, Neumann-Haefelin C, Klocperk A, Warnatz K, Hofmann M, Thimme R, Boettler T. 2020. IL-2 contributes to cirrhosis-associated immune dysfunction by impairing follicular T helper cells in advanced cirrhosis. J Hepatol. S0168-8278(20)33692-8. doi: 10.1016/j.jhep.2020.10.012.

Borst, K., and M. Prinz. 2020. Deciphering the heterogeneity of myeloid cells during neuroinflammation in the single cell era. Brain Pathol. doi: 10.1111/bpa.12910. Online ahead of print.

Fixemer J, Hummel JF, Arnold F, Klose CSN, Hofherr A, Weissert K, Kögl T, Köttgen M, Arnold SJ, Aichele P, Tanriver Y. 2020. Eomes cannot replace its paralog T-bet during expansion and differentiation of CD8 effector T cells. PLoS Pathog. 16(9):e1008870. doi: 10.1371/journal.ppat.1008870.

Thangavelu, G., C. Wang, M. Loschi, A. Saha, M. Osborn, S. N. Furlan, K. Aoyama, C. McDonald-Hyman, E. G. Aguilar, A. S. Janesick, R. A. Chandraratna, Y. Refaeli, A. Panoskaltsis-Mortari, K. P. MacDonald, G. R. Hill, R. Zeiser, I. Maillard, J. Serody, W. J. Murphy, D. H. Munn, B. Blumberg, C. Brown, V. K. Kuchroo, L. S. Kean, K. Hippen, R. J. Noelle, and B. R. Blazar. 2020. Repurposing a novel anti-cancer RXR agonist to attenuate acute GVHD and maintain graft-versus-leukemia responses. Blood. 137(8):1090-1103. doi: 10.1182/blood.2020005628.

Bornert O, Hogervorst M, Nauroy P, Bischof J, Swildens J, Athanasiou I, Tufa SF, Keene DR, Kiritsi D, Hainzl S, Murauer EM, Marinkovich MP, Platenburg G, Hausser I, Wally V, Ritsema T, Koller U, Haisma EM, Nyström A. 2020. QR-313, an Antisense Oligonucleotide, Shows Therapeutic Efficacy for Treatment of Dominant and Recessive Dystrophic Epidermolysis Bullosa: A Preclinical Study.  J Invest Dermatol. S0022-202X(20)32061-3. doi: 10.1016/j.jid.2020.08.018. Online ahead of print.

Bassett DS, Cullen KE, Eickhoff SB, Farah MJ, Goda Y, Haggard P, Hu H, Hurd YL, Josselyn SA, Khakh BS, Knoblich JA, Poirazi P, Poldrack RA, Prinz M, Roelfsema PR, Spires-Jones TL, Sur M, Ueda HR. 2020. Reflections on the past two decades of neuroscience. Nat Rev Neurosci. doi: 10.1038/s41583-020-0363-6. Online ahead of print.