Publications

Fliegauf M, Krüger R, Steiner S, Hanitsch LG, Büchel S, Wahn V, von Bernuth H, Grimbacher B. 2021. A Pathogenic Missense Variant in NFKB1 Causes Common Variable Immunodeficiency Due to Detrimental Protein Damage. Front Immunol. 12:621503.

Hatscher L, Lehmann CHK, Purbojo A, Onderka C, Liang C, Hartmann A, Cesnjevar R, Bruns H, Gross O, Nimmerjahn F, Ivanović-Burmazović I, Kunz M, Heger L, Dudziak D. 2021. Select hyperactivating NLRP3 ligands enhance the TH1- and TH17-inducing potential of human type 2 conventional dendritic cells. Sci Signal. 14(680):eabe1757.

Mertens, J., J. R. Herdy, L. Traxler, S. T. Schafer, J. C. M. Schlachetzki, L. Bohnke, D. A. Reid, H. Lee, D. Zangwill, D. P. Fernandes, R. K. Agarwal, R. Lucciola, L. Zhou-Yang, L. Karbacher, F. Edenhofer, S. Stern, S. Horvath, A. C. M. Paquola, C. K. Glass, S. H. Yuan, M. Ku, A. Szucs, L. S. B. Goldstein, D. Galasko, and F. H. Gage. 2021. Age-dependent instability of mature neuronal fate in induced neurons from Alzheimer’s patients. Cell Stem Cell. S1934-5909(21)00161-2.

Micheau O, Rizzi M, Smulski CR. 2021. Editorial: TNFR Superfamily Oligomerization and Signaling. Front Cell Dev Biol. 9:682472.

Gámez-Díaz L, Grimbacher B. 2021. Immune checkpoint deficiencies and autoimmune lymphoproliferative syndromes. Biomed J. 19:S2319-4170(21)00038-X. doi: 10.1016/j.bj.2021.04.005.

Neuwirt E, Gorka O, Saller BS, Groß CJ, Madl T, Groß O. 2021. NLRP3 as a sensor of metabolism gone awry. Curr Opin Biotechnol. 68:300-309.

Hartl, F. A., J. Ngoenkam, E. Beck-Garcia, L. Cerqueira, P. Wipa, P. Paensuwan, P. Suriyaphol, P. Mishra, B. Schraven, S. Gunther, S. Pongcharoen, W. W. A. Schamel, and S. Minguet. 2021. Cooperative Interaction of Nck and Lck Orchestrates Optimal TCR Signaling. Cells 10(4):834.

Wang, L., D. Aschenbrenner, Z. Zeng, X. Cao, D. Mayr, M. Mehta, M. Capitani, N. Warner, J. Pan, L. Wang, Q. Li, T. Zuo, S. Cohen-Kedar, J. Lu, R. C. Ardy, D. J. Mulder, D. Dissanayake, K. Peng, Z. Huang, X. Li, Y. Wang, X. Wang, S. Li, S. Bullers, A. N. Gammage, K. Warnatz, A. I. Schiefer, G. Krivan, V. Goda, W. H. A. Kahr, M. Lemaire, C. Genomics England Research, C. Y. Lu, I. Siddiqui, M. G. Surette, D. Kotlarz, K. R. Engelhardt, H. R. Griffin, R. Rottapel, H. Decaluwe, R. M. Laxer, M. Proietti, S. Hambleton, S. Elcombe, C. H. Guo, B. Grimbacher, I. Dotan, S. C. Ng, S. A. Freeman, S. B. Snapper, C. Klein, K. Boztug, Y. Huang, D. Li, H. H. Uhlig, and A. M. Muise. 2021. Gain-of-function variants in SYK cause immune dysregulation and systemic inflammation in humans and mice. Nat Genet 53: 500-510.

Nauroy, P., and D. Kiritsi. 2021. Research in practice: Towards deciphering the role of epidermal proteases in recessive dystrophic epidermolysis bullosa progression. J Dtsch Dermatol Ges. doi: 10.1111/ddg.14396.

Emig, R., W. Knodt, M. J. Krussig, C. M. Zgierski-Johnston, O. Gorka, O. Gross, P. Kohl, U. Ravens, and R. Peyronnet. 2021. Piezo1 Channels Contribute to the Regulation of Human Atrial Fibroblast Mechanical Properties and Matrix Stiffness Sensing. Cells 10: 663.

Globig, A. M., M. Heeg, C. S. Larsen, R. D. Ferreira, G. Kindle, S. Goldacker, V. Strohmeier, S. L. Silva, C. Cunningham-Rundles, I. Quinti, R. Thimme, D. Bettinger, M. Schultheiss, and K. Warnatz. 2021. International multicenter experience of transjugular intrahepatic portosystemic shunt implantation in patients with common variable immunodeficiency. J Allergy Clin Immunol Pract. 13:S2213-2198(21)00301-9.

Ehl, S., T. von Bahr Greenwood, E. Bergsten, A. Fischer, J. I. Henter, M. Hines, K. Lehmberg, G. Janka, D. Moshous, and K. E. Nichols. Is neutralization of IFN-gamma sufficient to control inflammation in HLH? Pediatr Blood Cancer 68: e28886.

Kohler, N., D. A. Ruess, R. Kesselring, and R. Zeiser. 2021. The Role of Immune Checkpoint Molecules for Relapse After Allogeneic Hematopoietic Cell Transplantation. Front Immunol 12: 634435.

Morimoto R, Swann J, Nusser A, Trancoso I, Schorpp M, Boehm T. 2021.  Evolution of thymopoietic microenvironments. Open Biol. 11(2):200383. doi: 10.1098/rsob.200383.

Camacho-Ordonez N, Ballestar E, Timmers HTM, Grimbacher B. 2021. What can clinical immunology learn from inborn errors of epigenetic regulators? J Allergy Clin Immunol. 147(5):1602-1618. doi: 10.1016/j.jaci.2021.01.035. Epub 2021 Feb 17.

Kläsener K, Jellusova J, Andrieux G, Salzer U, Böhler C, Steiner SN, Albinus JB, Cavallari M, Süß B, Voll RE, Boerries M, Wollscheid B, Reth M. 2021. CD20 as a gatekeeper of the resting state of human B cells. Proc Natl Acad Sci U S A. 118(7):e2021342118.