Publications

Hulsdunker, J., O. S. Thomas, E. Haring, S. Unger, N. Gonzalo Nunez, S. Tugues, Z. Gao, S. Duquesne, C. Cywes-Bentley, O. Oyardi, S. Kirschnek, A. Schmitt-Graeff, O. Pabst, C. Koenecke, J. Duyster, P. Apostolova, M. J. Blaser, B. Becher, G. B. Pier, G. Hacker, and R. Zeiser. 2019. Immunization against poly-N-acetylglucosamine reduces neutrophil activation and GVHD while sparing microbial diversity. Proc Natl Acad Sci USA 116: 20700-20706.

Heim, K., Neumann-Haefelin, R. Thimme, and M. Hofmann. 2019. Heterogeneity of HBV-Specific CD8(+) T-Cell Failure: Implications for Immunotherapy. Front Immunol 10: 2240.

Dorjbal B, Stinson JR, Ma CA, Weinreich MA, Miraghazadeh B, Hartberger JM, Frey-Jakobs S, Weidinger S, Moebus L, Franke A, Schäffer AA, Bulashevska A, Fuchs S, Ehl S, Limaye S, Arkwright PD, Briggs TA, Langley C, Bethune C, Whyte AF, Alachkar H, Nejentsev S, DiMaggio T, Nelson CG, Stone KD, Nason M, Brittain EH, Oler AJ, Veltri DP, Leahy TR, Conlon N, Poli MC, Borzutzky A, Cohen JI, Davis J, Lambert MP, Romberg N, Sullivan KE, Paris K, Freeman AF, Lucas L, Chandrakasan S, Savic S, Hambleton S, Patel SY, Jordan MB, Theos A, Lebensburger J, Atkinson TP, Torgerson TR, Chinn IK, Milner JD, Grimbacher B, Cook MC, Snow AL. 2019. Hypomorphic caspase activation and recruitment domain 11 (CARD11) mutations associated with diverse immunologic phenotypes with or without atopic disease. J Allergy Clin Immunol. 143(4):1482-1495.

Neumann-Haefelin C. 2019. Paving the way for T cell-based immunotherapies in chronic hepatitis E. J Hepatol. 71(4):648-650.

Kierdorf K, Masuda T, Jordão MJC, Prinz M. 2019. Macrophages at CNS interfaces: ontogeny and function in health and disease. Nat Rev Neurosci. 20(9):547-562. Review.

Fiala GJ, Schaffer AM, Merches K, Morath A, Swann J, Herr LA, Hils M, Esser C, Minguet S, Schamel WWA. 2019. Proximal Lck Promoter-Driven Cre Function Is Limited in Neonatal and Ineffective in Adult γδ T Cell Development. J Immunol. 203(2):569-579.

Bradley KC, Finsterbusch K, Schnepf D, Crotta S, Llorian M, Davidson S, Fuchs SY, Staeheli P, Wack A. 2019. Microbiota-Driven Tonic Interferon Signals in Lung Stromal Cells Protect from Influenza Virus Infection. Cell Rep. 28(1):245-256.

Alfei, F., K. Kanev, M. Hofmann, M. Wu, H. E. Ghoneim, P. Roelli, D. T. Utzschneider, M. von Hoesslin, J. G. Cullen, Y. Fan, V. Eisenberg, D. Wohlleber, K. Steiger, D. Merkler, M. Delorenzi, P. A. Knolle, C. J. Cohen, R. Thimme, B. Youngblood, and D. Zehn. 2019. TOX reinforces the phenotype and longevity of exhausted T cells in chronic viral infection. Nature 571: 265-269. doi: 10.1038/s41586-019-1326-9.

Vandrovcova J, Salzer U, Grimbacher B, Wanders J, Rao K, Thrasher A, Burns S, Gilmore K, Bussel J, Cooper N. 2019. FAS mutations are an uncommon cause of immune thrombocytopenia in children and adults without additional features of immunodeficiency. Br J Haematol. 186(6):e163-e165.

Schamel, W. W., B. Alarcon, and S. Minguet. 2019. The TCR is an allosterically regulated macromolecular machinery changing its conformation while working. Immunol Rev 291: 8-25.

Dettmer, V., K. Bloom, M. Gross, K. Weissert, Aichele, S. Ehl, and T. Cathomen. 2019. Retroviral UNC13D gene transfer restores cytotoxic activity of T cells derived from familial hemophagocytic lymphohistiocytosis type 3 patients in vitro. Hum Gene Ther. 30(8): 975-984.

Qiu, J., M. Villa, D. E. Sanin, M. D. Buck, D. O’Sullivan, R. Ching, M. Matsushita, K. M. Grzes, F. Winkler, C. H. Chang, J. D. Curtis, R. L. Kyle, N. Van Teijlingen Bakker, M. Corrado, F. Haessler, F. Alfei, J. Edwards-Hicks, L. B. Maggi, Jr., D. Zehn, T. Egawa, B. Bengsch, R. I. Klein Geltink, T. Jenuwein, E. J. Pearce, and E. L. Pearce. 2019. Acetate Promotes T Cell Effector Function during Glucose Restriction. Cell Rep 27: 2063-2074 e2065.

Lorenzetti R, Janowska I, Smulski CR, Frede N, Henneberger N, Walter L, Schleyer MT, Hüppe JM, Staniek J, Salzer U, Venhoff A, Troilo A, Voll RE, Venhoff N, Thiel J, Rizzi M. 2019. Abatacept modulates CD80 and CD86 expression and memory formation in human B-cells. J Autoimmun. 101:145-152.

Staniek J, Lorenzetti R, Heller B, Janowska I, Schneider P, Unger S, Warnatz K, Seidl M, Venhoff N, Thiel J, Smulski CR, Rizzi M. 2019. TRAIL-R1 and TRAIL-R2 Mediate TRAIL-Dependent Apoptosis in Activated Primary Human B Lymphocytes. Front Immunol. 10:951.

von Spee-Mayer, C., V. Koemm, C. Wehr, S. Goldacker, G. Kindle, A. Bulashevska, M. Proietti, Grimbacher, S. Ehl, and K. Warnatz. 2019. Evaluating laboratory criteria for combined immunodeficiency in adult patients diagnosed with common variable immunodeficiency. Clin Immunol. 203:59-62.

Eskandarian, Z., M. Fliegauf, A. Bulashevska, M. Proietti, R. Hague, C. R. Smulski, D. Schubert, Warnatz, and B. Grimbacher. 2019. Assessing the Functional Relevance of Variants in the IKAROS Family Zinc Finger Protein 1 (IKZF1) in a Cohort of Patients With Primary Immunodeficiency. Front Immunol 10: 568.