Publications

Ott N, Faletti L, Heeg M, Andreani V, Grimbacher B. 2023. JAKs and STATs from a Clinical Perspective: Loss-of-Function Mutations, Gain-of-Function Mutations, and Their Multidimensional Consequences. J Clin Immunol. 2023 May 4. doi: 10.1007/s10875-023-01483-x.

Cox EM, El-Behi M, Ries S, Vogt JF, Kohlhaas V, Michna T, Manfroi B, Al-Maarri M, Wanke F, Tirosh B, Pondarre C, Lezeau H, Yogev N, Mittenzwei R, Descatoire M, Weller S, Weill JC, Reynaud CA, Boudinot P, Jouneau L, Tenzer S, Distler U, Rensing-Ehl A, König C, Staniek J, Rizzi M, Magérus A, Rieux-Laucat F, Wunderlich FT, Hövelmeyer N, Fillatreau S. 2023.  AKT activity orchestrates marginal zone B cell development in mice and humans. Cell Rep. 2023 Apr 14;42(4):112378. doi: 10.1016/j.celrep.2023.112378.

Staus P, Rusch S, El-Helou S, Müller G, Krausz M, Geisen U, Caballero-Oteyza A, Krüger R, Bakhtiar S, Lee-Kirsch MA, Fasshauer M, Baumann U, Hoyer BF, Farela Neves J, Borte M, Carrabba M, Hauck F, Ehl S, Bader P, von Bernuth H, Atschekzei F, Seppänen MRJ, Warnatz K, Nieters A, Kindle G, Grimbacher B. 2023.  The GAIN Registry – a New Prospective Study for Patients with Multi-organ Autoimmunity and Autoinflammation. J Clin Immunol. Apr 21:1-13. doi: 10.1007/s10875-023-01472-0.

Luxenburger H, Reeg DB, Lang-Meli J, Reinscheid M, Eisner M, Bettinger D, Oberhardt V, Salimi Alizei E, Wild K, Graeser A, Karl V, Sagar, Emmerich F, Klein F, Panning M, Huzly D, Bengsch B, Boettler T, Elling R, Thimme R, Hofmann M, Neumann-Haefelin C. 2023. Boosting compromised SARS-CoV-2-specific immunity with mRNA vaccination in liver transplant recipients. J Hepatol. Feb 18:S0168-8278(23)00095-8. doi: 10.1016/j.jhep.2023.02.007.

Nöltner C, Bulashevska A, Hübscher K, Haberstroh H, Grimbacher B, Proietti M. 2023. Fecal Immunoglobulin Levels as a Modifier of the Gut Microbiome in Patients with Common Variable Immunodeficiency. J Clin Immunol. Mar 24. doi: 10.1007/s10875-023-01469-9.

Mass E, Nimmerjahn F, Kierdorf K, Schlitzer A. 2023. Tissue-specific macrophages: how they develop and choreograph tissue biology.  Nat Rev Immunol.  Mar 15:1-17. doi: 10.1038/s41577-023-00848-y.

Villa M, Sanin DE, Apostolova P, Corrado M, Kabat AM, Cristinzio C, Regina A, Carrizo GE, Rana N, Stanczak MA, Baixauli F, Grzes KM, Cupovic J, Solagna F, Hackl A, Globig AM, Hässler F, Puleston DJ, Kelly B, Cabezas-Wallscheid N, Hasselblatt P, Bengsch B, Zeiser R, Sagar, Buescher JM, Pearce EJ, Pearce EL. 2023. Prostaglandin E 2 controls the metabolic adaptation of T cells to the intestinal microenvironment. bioRxiv. Mar 15:2023.03.13.532431. doi: 10.1101/2023.03.13.532431.

Greve G, Andrieux G, Schlosser P, Blagitko-Dorfs N, Rehman UU, Ma T, Pfeifer D, Heil G, Neubauer A, Krauter J, Heuser M, Salih HR, Döhner K, Döhner H, Hackanson B, Boerries M, Lübbert M. 2023. In vivo kinetics of early, non-random methylome and transcriptome changes induced by DNA-hypomethylating treatment in primary AML blasts. Leukemia. 2023 Apr 6. doi: 10.1038/s41375-023-01876-2.

Paul MC, Schneeweis C, Falcomatà C, Shan C, Rossmeisl D, Koutsouli S, Klement C, Zukowska M, Widholz SA, Jesinghaus M, Heuermann KK, Engleitner T, Seidler B, Sleiman K, Steiger K, Tschurtschenthaler M, Walter B, Weidemann SA, Pietsch R, Schnieke A, Schmid RM, Robles MS, Andrieux G, Boerries M, Rad R, Schneider G, Saur D. 2023. Non-canonical functions of SNAIL drive context-specific cancer progression. Nat Commun. Mar 7;14(1):1201. doi: 10.1038/s41467-023-36505-0.

Isbell LK, Tschuch C, Doostkam S, Waldeck S, Andrieux G, Shoumariyeh K, Lenhard D, Schaefer HE, Reinacher PC, Bartsch I, Pantic M, Vinnakota JM, Kakkassery V, Schorb E, Scherer F, Frey AV, Boerries M, Illerhaus G, Duyster J, Schueler J, von Bubnoff N. 2023. Patient-derived xenograft mouse models to investigate tropism to the central nervous system and retina of primary and secondary central nervous system lymphoma. Neuropathol Appl Neurobiol. Mar 6:e12899. doi: 10.1111/nan.12899.

Dieter K, Niebergall-Roth E, Daniele C, Fluhr S, Frank NY, Ganss C, Kiritsi D, McGrath JA, Tolar J, Frank MH, Kluth MA.2023.  ABCB5+ mesenchymal stromal cells facilitate complete and durable wound closure in recessive dystrophic epidermolysis bullosa. Cytotherapy. Mar 1:S1465-3249(23)00036-1. doi: 10.1016/j.jcyt.2023.01.015.

Lim YW, Ramirez NJ, Asensio MA, Chiang Y, Müller G, Mrovecova P, Mitsuiki N, Krausz M, Camacho-Ordonez N, Warnatz K, Adler AS, Grimbacher B. 2023. Sequencing the B Cell Receptor Repertoires of Antibody-Deficient Individuals With and Without Infection Susceptibility.  J Clin Immunol. Feb 24. doi: 10.1007/s10875-023-01448-0.

Rhiel M, Geiger K, Andrieux G, Rositzka J, Boerries M, Cathomen T, Cornu TI. 2023. T-CAST: An optimized CAST-Seq pipeline for TALEN confirms superior safety and efficacy of obligate-heterodimeric scaffolds. Front Genome Ed. Feb 20;5:1130736. doi: 10.3389/fgeed.2023.1130736.

Schauer F, Tasiopoulou G, Schuster D, Behrens M, Müller S, Kiritsi D. 2023. Primate liver tissue substrate in indirect immunofluorescence diagnostics for patients with dermatitis herpetiformis and celiac disease. Front Immunol. Feb 16;14:1104360. doi: 10.3389/fimmu.2023.1104360.

Fox T, Bueren J, Candotti F, Fischer A, Aiuti A, Lankester A; AGORA Initiative; Booth C. Access to gene therapy for rare diseases when commercialization is not fit for purpose. Nat Med. 2023 Feb 13. doi: 10.1038/s41591-023-02208-8.

Amann L, Masuda T, Prinz M. Mechanisms of myeloid cell entry to the healthy and diseased central nervous system. Nat Immunol. 2023 Feb 9. doi: 10.1038/s41590-022-01415-8.